Award Data

Addressing the needs of Mars exploration missions in the NASArsquo;s strategic plan will require robust and effective autonomous collaborative operations between heterogeneous assets. These ldquo;swarmsrdquo; may consisting of ground rovers, atmospheric craft and Mars-orbiting satellites. To maximize the satisfaction of overall mission objectives, be tolerant of faults/anomalies, and minimize the ...

Technology currently used for terrestrial navigation is extremely limited in the challenging environments on icy moons and ocean worlds such as Europa. Autonomous platforms used to collect data from beneath these ice and ocean surfaces cannot depend on access to satellite or any other electromagnetic communication. Autonomous systems in these environments are required to perform highly-complex tas ...

Project Summary AbstractThe recent rapid expansion of genomic data greatly contributes to the understanding of disease development and progressionTo translate these genetic discoveries into clinical applicationswe need to develop therapeutic platforms that can specifically modulate the expression of disease related genes in vivoSmall RNAssuch as microRNAs and siRNAs function in messenger RNA silen ...

AbstractIf there were a simple and accurate means totake the pulseof a toothi efunctionally similar to a pulse oximeter that could be clipped on a tooth rather than the tip of a fingerthe quality and cost of dental care would be significantly improvedThe ability to measure dental pulp blood flow provides the most direct means to determine the viability of a tooth and is a vital piece of informatio ...

Spectral Energies proposes to design a multisensory diagnostic suite for measurements within elevated-pressure RDEs. This sensor will utilize tunable-laser absorption spectroscopy to measure temperature, pressure and H2O concentrations in the annulus of a rocket-RDE and background-oriented schlieren imaging system for flow density gradient imaging to provide time resolved information about the sho ...

In this program, Morton Photonics (MP) and its STTR partner Professor John Bowers and his research group at the University of California at Santa Barbara (UCSB) will develop two truly disruptive integrated laser devices: (1) A broadly tunable integrated laser with ultra-low linewidth, ultra-low relative intensity noise (RIN), and high output power; the Integrated Coherent Tunable Laser (ICTL), whi ...

Myocardial infarctionsMIor heart attacksischemic strokesISand peripheral artery diseasePADtogether considered cardiovascular diseaseCVDare all commonly caused by the same underlying pathologyatherosclerosisMIs and ISs are the leading causes of death and disability worldwideAtherosclerosis is a progressive pathology that develops asymptomatically over the course of many years as inflammatory plaque ...

SUMMARYParkinsonandapos s diseasePDis the second most prevalent neurodegenerative disorder after Alzheimerandapos s diseaseADaffecting more thanmillion people in the United StatesBecause age is the major risk factorthe prevalence of both diseases is steadily increasing as our population agesPD belongs to the group of protein misfolding neurodegenerative diseases that are due to the misfolding and ...

ABSTRACTSubstance use disordersSUDsincluding opioid use disorderscontinue to be one of the most serious public health issues in the USleading to negative physical and mental health problemsfamily disruptionand premature deathAfrican Americans with drug use histories that are under criminal justice supervision are particularly vulnerable to experiencing the negative consequences associated with SUD ...

AbstractThe focus of this proposal is the development of therapy to protect the lung with an extracellular anti oxidant defense to treat chronic obstructive pulmonary diseaseCOPDa chronic disorder in which inhaled oxidants from tobacco smokepollution and generated within the lung by activated inflammatory cells perpetuate injury to the lung epithelium and endotheliumThe LEXEO strategy is to use in ...