Award Data

This STTR Phase II project will develop novel engineered Clostridia strains for fermentation and economically produce butanol as a biofuel from sugars derived from starchy and lignocellulosic biomass. The conventional acetone-butanol-ethanol (ABE) fermentation has low butanol yield (

We present a comprehensive framework for modeling, optimization and design for heterogeneous networks. The proposed solution aims to effectively address the existing limitations inherited from the generalized network utility maximization (GNUM) framework. In general, GNUM is a unifying mathematical model as it combines different objectives and constraints from different layers into a single global ...

Two-dimensional (2D) visualization techniques have limit capacity to achieve understanding of full dimensionality of the battlefield. Rewritable 3D holographic storage is promising for updatable 3D display applications. In Phase I, New Span Opto-Technology has demonstrated novel concepts of both holographic recording technique and recording material system without the use of high voltage. We have ...

We propose the development of a system for measuring the minority carrier lifetime in strained layer superlattices (SLS). Mid wave infrared (MWIR) and long wave infrared (LWIR) detectors based on SLS technology show promise due to the large and inexpensive focal plane arrays that can be fabricated. The devices are held back though, by excessive dark current, which is related to a poor minority car ...

In this Phase I STTR, Illuminaria, in collaboration with Professor Erickson’s Laboratory at Cornell University, designed and developed a practical liquid based reconfigurable photonic device photonic switch using low voltage microfluidic pumps and microfabricated optofluidic waveguides. Briefly, the basic element of this approach comprises a stream of high index of refraction liquid (core) micr ...

DESCRIPTION (provided by applicant): The long term objective of this project is to enable elderly persons to independently live within their own homes later into their lives with the assurance that their safety and well-being can be remotely monitored by health care professionals. A critical component of remote health care monitoring is physically tracking the location of the patient within a livi ...

DESCRIPTION (provided by applicant): The goals of this proposal are to devise rapid serological tests that can replace the sputum smear test for the diagnosis of active TB and meets the WHO specifications to replace microscopy in resource-limited countries based on immunodominant peptides from three M. tb cell-wall proteins. Although direct smear microscopy is highly specific, the test is tedious, ...

DESCRIPTION (provided by applicant): Genital herpes is one of the most prevalent sexually transmitted infections worldwide and is associated with substantial morbidity. The impact of genital herpes as a public health threat is amplified because of its epidemiologic synergy with HIV. Epidemiological studies consistently demonstrate that HSV infection increases the risk of HIV transmission and acqu ...

DESCRIPTION (provided by applicant): Osteoarthritis (OA) is the leading cause of chronic disability in the United States. A clinical goal in the treatment and prevention of OA is to develop replacement cartilage using tissue engineering (TE) technologies. Although TE cartilage presently lacks the mechanical stability of native cartilage, studies have demonstrated that mechanical stability can be e ...

DESCRIPTION (provided by applicant): Prostate cancer is the second most common cancer in men, and the second leading cause of cancer death. However, when prostate cancer is diagnosed in its early stages, it can be effectively treated and cured. Combined with the digital rectal examination, the prostate specific antigen (PSA) test has been widely used to detect prostate cancer in its early stages. ...