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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Development of a Genotype-linked Antibiotic Resistance Platform for Real Time Pathogen Risk Classification and Epidemiology

    SBC: MAVERIX BIOMICS, INC.            Topic: NIAID

    Project Summary Antibiotic resistance has become a pressing public health concern due to the rise of pathogenic bacterial strains with mutations that reduce or eliminate the effectiveness of drugs to treat infections Beta lactamases produced by some bacteria provide resistance by degrading beta lactams one of most widely used class of antibiotics Originally restricted to penicillins mutant bet ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  2. Development of Optimized Endectocide-treated Bird Feed Formulations for West Nile Virus Control

    SBC: TDA RESEARCH, INC.            Topic: NIAID

    Project Summary Abstract Development of Optimized Endectocide treated Bird Feed Formulations for West Nile Virus Control STTR Phase I Application PIs Brady Clapsaddle TDA Research Inc Dr Brian Foy Colorado State University West Nile Virus WNV is the leading cause of domestically acquired arboviral disease in the United States resulting in significant disease and death every year in both ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  3. Blockade of histamine-releasing factor as a new prophylactic and therapeutic strategy for food allergy

    SBC: ABWIZ BIO INC            Topic: NIAID

    DESCRIPTION provided by applicant The prevalence of food allergy has been dramatically increasing for the last few decades Food Allergy and Anaphylaxis Network www foodallergy org estimates that up to million Americans have food allergies Six to eight percent of children under the age of three have food allergies and nearly four percent of adults have them Signs and symptoms of food all ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  4. Reagents to Create Large DNA Constructs in One Assembly Step

    SBC: FIREBIRD BIOMOLECULAR SCIENCES LLC            Topic: 100

    DESCRIPTION provided by applicant To many notably Craig Venter andquot synthetic biologyandquot means simply andquot synthesizing large amounts of DNAandquot This type of synthetic biology actually began in the andapos s when Caruthers introduced a phosphoramidite based solid phase DNA synthesis architecture This allowed ICI and the Benner group to synthesize complete genes encoding ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Commercial Polymerases to Create Receptors, Ligands, and Catalysts on Demand

    SBC: FIREBIRD BIOMOLECULAR SCIENCES LLC            Topic: NIGMS

    Commercial Polymerases to Create Receptors Ligands and Catalysts on Demand Firebird Biomolecular Sciences LLC University of Texas Steven A Benner Andrew D Ellington ABSTRACT Innovators at Firebird Biomolecular Sciences LLC have created several generations of an artificially ex panded genetic information system AEGIS that adds eight nucleobases that form four additional pairs Z P S ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  6. An Agent-Based Modeling Platform for Environmental Biotechnology

    SBC: MICROVI BIOTECH, INC.            Topic: NIEHS

    DESCRIPTION provided by applicant Hazardous compounds in waters and soils are subject to a complex dynamic web of interactions among physical chemical and biological constituents in the natural environment Computational modeling has been proven indispensable to hazardous substances remediation particularly integrated modeling of pollutant hydrogeological fate and transport For the first t ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  7. Advanced Polymer-Based Micro-sensor for Radiation Detection and Measurement

    SBC: SEACOAST SCIENCE, INC.            Topic: NIEHS

    Project Summary This Small Business Technology Transfer Phase I project proposes the development and optimization of a commercially viable novel polymer based radiation dosimeter for wide spread deployment The radiation dosimeter proposed herein is a disruptive technology with a significant market Although many commercial radiation dosimeters measure individual radiation load dose quantificatio ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  8. Evaluation of SBP-101 for the Treatment of Acute Pancreatitis

    SBC: SUN BIOPHARMA, INC.            Topic: 300

    Project Summary Pancreatitis is a significant public health problem accounting for over $ Billion of health care costs annually Approximately one third of patients with acute pancreatitis will go on to have recurrent pancreatitis Of those about will progress to chronic pancreatitis a painful disease with an increased risk of both diabetes and pancreatic cancer More than of people w ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  9. Nanoliter electron paramagnetic resonance sensor based on diamond nanophotonics: a new tool for biomarker monitoring

    SBC: ODMR Technologies, Inc            Topic: 400

    DESCRIPTION provided by applicant ODMR Technologies Inc together with Victor Acostaandapos s group at University of New Mexico is developing a nanophotonic platform capable of uniquely detecting minute quantities of biomolecules The specific detection of biomolecules plays a central role in modern life science including cell systems biology high throughput drug scre ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  10. PreImplantation Factor plus hypothermia to treat neonatal brain injury

    SBC: BioIncept, LLC            Topic: NICHD

    ABSTRACT Perinatal hypoxic ischemic encephalopathy HIE affects to infants per every born Mortality from HIE can be up to and approximately of survivors suffer significant long term disability including cerebral palsy epilepsy and developmental disorders Damage during the acute phase of HIE is caused by a deficit in oxygen and glucose in the brain However increasing evide ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
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