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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Matrix Metalloproteinase-2/-9 Inhibitor For The Treatment Of ALS

    SBC: AQUILUS PHARMACEUTICALS INC            Topic: 103

    Project Summary AbstractAquilus PharmaceuticalsIncproposes to evaluate the effects of a selectivedual activematrix metalloproteinaseMMPand MMPinhibitorAQUin the superoxide dismutaseSODmouse model of amyotrophic lateral sclerosisALSThe goals for Phase I are to chemically synthesize AQUdetermine its oral pharmacokineticsPKin SODmice and then determine its efficacy in the SODmouse model of ALS with d ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. Preventing Opioid Exposure Training (POET) for First Responders

    SBC: GRYPHON SCIENTIFIC, LLC            Topic: 142

    PROJECT SUMMARY/ABSTRACT In this competitive revision Phase I SBIR, Gryphon Scientific proposes to expand the scope of the ongoing project to support the urgent need to develop and deploy training for first responder populations at risk of exposure to the novel coronavirus (COVID-19). The ongoing Phase I SBIR project focuses on training first responders (including law enforcement, fire, and EMS pe ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Human Milk Concentration Device; Point of Care Technology for Feeding Preterm Infants in Intensive Care

    SBC: MOTHER'S MILK IS BEST, INC.            Topic: NICHD

    Human milk is the best feeding option for preterm infantsHoweverdue to the high nutrient needs of preterm infants in US Neonatal Intensive Care UnitsNICUsthe mother s own milk is most often mixed with bovine milk sourced fortifiers to achieve goal nutrient levelsThe Human Milk ConcentrationHMCdevice concentrates a mother s milk by removing water so that preterm infants can receive adequate nutrien ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Safety using Augmented reality to Facilitate Effective Training and Education (SAFE-TE). The objective of SAFE-TE is to support workers being trained to work with hazardous materials more efficiently

    SBC: BENTEN TECHNOLOGIES, INC.            Topic: NIEHS

    PROJECT SUMMARY ABSTRACT The Occupational Safety and Health ActOSHAwas formed to protect workers and prevent work related injuriesOSHA standards include explicit safety and health training requirements to ensure that the workers have required skills and knowledge to do their work safelyBenten Technologies is partnering with the International Brotherhood of TeamstersIBTto help workers in the HAZMAT ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Portable Ankle Robotics to Reverse Foot Drop After Stroke.

    SBC: NEXTSTEP ROBOTICS, INC.            Topic: NINDS

    This proposal finalizes the design of a portable ankle robot as a therapeutic device to reverse foot drop and restore safer independent walking after stroke, then conducts a rigorous randomized clinical trial to establish clinical proof for this new market application. Currently, there are no therapeutic solutions for foot-drop, only assistive devices (braces, canes, electrical stimulation) that d ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Targeting a double fail-safe construct to prevent tumorigenesis and select pancreatic endocrine cells from human embryonic stem cells

    SBC: Ophysio Inc.            Topic: 400

    PROJECT SUMMARYHuman embryonic stem cellshEScrepresent a potentially unlimited supply of tissues for regenerative therapiesHowevercurrent differentiation methods result in heterogeneous populations of cells in which the desired product isat besta fraction of the totalMoreovercarry over undifferentiated cellsas well as cells that de differentiate upon transplantationhave been shown to form teratoma ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Direct-read monitor for airborne viral pathogens

    SBC: AEROSOL DEVICES INC            Topic: NIAID

    Aerosolized pathogenssuch as Influenza virusescan spread rapidly and silently throughout a populationcausing severe outbreaks that can be difficult to controlEarly detection of these airborne pathogens is key to controlling outbreaksespecially among vulnerable populations such as in hospitalstreatment centers or nursing homesYet available methods are neither rapidnor portableCurrent methods rely h ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Novel oral delivery system for subunit vaccine against ETEC

    SBC: FoodSource Lure Corporation            Topic: NIAID

    Project Summary Abstract Oral vaccines have the potential to make a revolutionary improvement in the quality of life in developing countriesSince these vaccines can be administered by community health workers who are not trained medical personnelthe number of people who can be immunized in a short period of time is drastically increased while the cost per patient is significantly loweredOral vacci ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Star-dots fluorescent nanoparticles for flow cytometry and biomedical imaging

    SBC: Nanoscience Solutions, LLC            Topic: NIAID

    Fluorescent nanoparticlesFNPare becoming increasingly popular in biomedical imaging and taggingCompared to molecule based fluorophoresFNP are typically brighter and more photostableThey can be functionalized with more than one tagging moleculeused for the tagging and tracing of specific moleculescellstissuesBrighter fluorescence facilitates more sensitive labelingand in many casesa lower limit of ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. An Advanced Lung Organomimetic to Reproduce Human Airway Pathophysiology

    SBC: PNEUMAX, LLC            Topic: 113

    PROJECT SUMMARYThree of top five causes of death in humans globally are lung relatedchronic obstructive pulmonary diseaseCOPDlower respiratory infections and lung cancers collectively account for over eight million deaths annuallyCurrentlyin preclinical settingstatic cell cultures and animal models are the most widely used systems for mechanistic and translational studiesHowevercritical limitation ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
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