Award Data

Approximately of all newborns worldwide risk permanent neurotoxic brain injury due severe neonatal jaundice SNJ This condition generally occurring in the first two weeks of life is almost always cured with high intensity blue light phototherapy In the United States most phototherapy is delivered in a neonatal intensive care unit NICU because effective high intensity devices have engi ...

As naval vessels increase capabilities for carrying out various missions, overall power requirements of these vessels continue to increase. Consequently, the power conversion equipment used to supply power throughout the ship increases in size, weight, and power. State-of-the-art electronics power density, including the thermal management system (TMS) is limited to approximately 0.5 MW per cubic m ...

GVD Corporation (GVD), in coordination with a major prime contractor, has developed a plan to demonstrate reliability without hermeticity (RWOH) for electronics packages to meet size, weight and cost requirements for UAV radars.The plan is enabled by GVD thin-film coatings which provide suitable environmental protection with negligible effect to RF performance. The proposed SBIR effort would produ ...

DESCRIPTION provided by applicant The goal of this Fast Track Phase I II SBIR is to test a novel extracorporeal system for delivering mesenchymal stem cell MSC secretions to treat acute myocardial infarction MI We will use the Sentien proprietary extracorporeal delivery system to treat swine subjected to a clinically relevant model of MI The project specific aims are Simulated blood ...

DESCRIPTION provided by applicant Toxicity accounts for approximately of drug attrition of which nearly one third is attributed to cardiovascular issues in particular arrhythmias The cost of bringing a new drug to market can exceed $ billion and require more than years of research Thus it is critical to identify cardiotoxicity early in developmen Current in vitro screening assa ...

DESCRIPTION provided by applicant Pediatric and neonatal airway management skills are life saving difficult to master and used infrequently enough to make skill maintenance a serious challenge For example multiple studies have shown that pediatric and neonatal intubation procedures are often successful less than half of the time especially among residents Given the long skill acquisition ...

DESCRIPTIONprovided by applicantThe goal of this Fast Track STTR project is to develop a novel CardioPortTM surgical device that will enable minimally invasive beating heart repair without use of cardiopulmonary bypassCPBThere is a critical unmet need for new instruments to improve the surgical repair of heart defects in childrenCurrent best surgical practices involve either open heart surgery wit ...

DESCRIPTION provided by applicant Platelet BioGenesis is developing a microfluidic bioreactor to produce human platelets at clinical scale Platelets are the andapos band aidsandapos of the bloodstream responsible for clot formation and blood vessel repair Low platelet count is a significant consequence of cancer treatment transplant and surgery for which platelets are a critical first li ...

Aerial refueling can be a dangerous mission, particularly when there is a failure in the tanker system or poor pilot technique on the receiver side. During these instances, sine waves can be developed in the hose that create loads that are damaging to both tanker and receiver aerial refueling systems. The primary objective of this Phase II.5 effort is to finish development and provide the necessar ...

The PSI Team will develop highly innovative hypersonic vehicle ceramic matrix composite (CMC) structures to significantly advance the state-of-the-art aeroshells that meet the flight requirements of hypersonic vehicles currently under design and are affordable. The PSI focus is to mature and demonstrate the technologies necessary to manufacture a fully integrated, structurally efficient loadbearin ...