Award Data

DESCRIPTION provided by applicant Sickle cell disease SCD is a global health issue that affects over million people worldwide including Americans SCD is a chronic and multifactorial disease which is characterized by a persistent milieu of oxidative stress inflammation and painful episodes of sickle crisis The Product and Long Term Goal Nanometics is developing a targeted sm ...

DESCRIPTION provided by applicant Multiple Sclerosis MS is a major neurological disease affecting over Americans and million worldwide Pathological studies suggest these numbers should be doubled In addition the number of people with MS is increasing especially in women The disease has a devastating impact and commonly produces disability in the motor cognitive and vocation ...

DESCRIPTION provided by applicant Solving human health problems often involves technologies developed through the collaborative work of scientists engineers and mathematicians Despite the fact that STEM science technology engineering and mathematics collaboration is a crucial aspect of biomedical research innovations many students are still learning science engineering and math as is ...

DESCRIPTION provided by applicant The purpose of the proposed project is to conduct a Phase a mechanistic clinical proof of concept study of an investigational drug T D which is being developed for the treatment of cognitive and functional decline in Alzheimerandapos s disease patients T D has successfully completed Phase I studies and with data demonstrating robust entry into the b ...

DESCRIPTION provided by applicant There are several features of ultrasound imaging that make it attractive to clinicians and preclinical researchers including its relatively low cost rel time imaging capability safety and portability For example ultrasound imaging is widely used for anatomical imaging and blood flow measurements in the heart and large vessels Ultrasound however is typi ...

DESCRIPTION provided by applicant The overall goal of the present study is to resurface a diseased femoral condyle in an ovine model of unicompartmental osteoarthritis OA For patients suffering from unicompartmental OA of the knee unicondylar knee arthroplasty UKA is an available first line treatment option that provides many potential advantages over more common total knee replacement p ...

DESCRIPTION provided by applicant Antibiotic resistance has been declared one of the three greatest threats to human health by the World Health Organization Infections caused by multi drug resistant MDR bacterial pathogens create substantial health and economic impacts on society due to the lack of effective therapeutic options created by the rapid acquisition of resistance and stagnant anti ...

DESCRIPTION provided by applicant In more than million people reported using prescription pain medications opioids non medically without a prescription and million people reported using prescription painkillers non medically for the first time In o people older than initiated illicit drug use via non medical use of prescription drugs Each year the prob ...

DESCRIPTION provided by applicant An epidemic of addiction to prescription pain medications now causes deaths due to overdose that outnumber automobile related deaths rising admissions to hospitals and disrupted lives for both the patient and family The White House Office of National Drug Control Policy ONDCP report Epidemic Responding to Americaandapos s Prescription Drug Abuse Crisis ...

DESCRIPTION provided by applicant Cigarette smoking remains the number one cause of preventable morbidity and mortality in the U S Each year one third to one half of smokers attempt to quit at least once however approximately of quit attempts fail A number of interventions have been developed to help smokers initiate and maintain abstinence Unfortunately even though most smokers expr ...