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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Development of the first HRV vaccine

    SBC: BIOLOGICAL MIMETICS, INC.            Topic: NIAID

    DESCRIPTION provided by applicant Human rhinoviruses HRV are the leading cause of common colds and virus induced exacerbation of asthma and chronic pulmonary diseases In addition HRV can cause severe lower respiratory tract infections in children the elderly and immune compromised patients The economic burden of the common cold is estimated to be about $ B each year in the US in terms o ...

    SBIR Phase II 2014 Department of Health and Human Services
  2. A Patient-Driven Rehabilitation System to Improve Upper Limb Amputee Outcomes

    SBC: Infinite Biomedical Technologies, LLC            Topic: NICHD

    DESCRIPTION provided by applicant A patient driven rehabilitation system to improve upper limb amputee outcomes The goal of our research program is to develop technological solutions that restore function for upper extremity amputees For these individuals one of the most promising developments in the past decade has been the introduction of fully dexterous terminal devices However an effe ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Laser Speckle Imaging Chip for Telehealth Applications

    SBC: Vasoptic Medical, Inc.            Topic: NIA

    DESCRIPTION provided by applicant There is a strong unmet need for a low cost and convenient technology that can assist researchers and healthcare personnel in gathering vascular data Such vascular imaging technology could assist in the short term clinica research on the diagnostics disease progression and effect of treatment prevention strategies ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. In vivo conjugated multivalent toxoid-polysaccharide vaccine for S. aureus

    SBC: Integrated Biotherapeutics, Inc.            Topic: NIAID

    DESCRIPTION provided by applicant Staphylococcus aureus is a Gram positive human pathogen that causes a wide range of infections from skin and soft tissue infections SSTI to life threatening sepsis and pneumonia The pathogenicity of S aureus is dependent on numerous virulence factors including cell surface proteins and polysaccharides as well as secreted toxins An important group of thes ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Catheter for Large Volume Intraparenchymal Brain Therapies

    SBC: TWIN STAR TDS, LLC            Topic: 105

    DESCRIPTION provided by applicant Neurodegenerative and malignant diseases of the central nervous system affect millions of Americans These diseases are often devastating and difficult to treat and effective drug delivery remains a significant challenge Infusion of drugs nto the brain parenchyma using convection enhanced delivery CED allows direct treatment of lesions circumventing the bl ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  6. College Alcohol Assessment and Intervention Training Simulation

    SBC: SIMmersion L.L.C.            Topic: 400

    DESCRIPTION provided by applicant The goal of this Phase I Phase II Fast Track application is to develop and evaluate a simulation based product for training student affairs staff e g resident assistants RAs Greek life staff campus and housing security student conduct staff and academic advisors to assess and provide appropriate intervention to students who engage in risky drinking be ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Circulating Blood-Based Diagnostic for Mild Cognitive Impaired Victims

    SBC: ADVANCED GENOMIC TECHNOLOGY, LLC            Topic: NIA

    DESCRIPTION provided by applicant This project aims to generate blood tests for mild cognitive impairment MCI and conversion risk from MCI to full blown Alzheimerandapos s disease AD We have reported that systemic footprints increases in key micro RNA miR levels are identifiable in AD blood samples here we suggest that this is also true for MCI the pre AD phase Our recent ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Novel High Affinity VEGF Analogs For Targeted Imaging of Thyroid Cancer

    SBC: TROPHOGEN INC            Topic: 102

    DESCRIPTION provided by applicant Thyroid cancer of follicular origin is the most common malignancy of endocrine tissues disproportionally affecting women and is one of the few cancers greatly increasing in incidence andamp prevalence for unknown reasons not solely attributable to improved diagnosis Most patients require lifelong diagnostic surveillance with radioiodine imaging to detect re ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  9. Development of a Motionless 3D Fluorescent Microscope

    SBC: Celloptic, Inc.            Topic: NCI

    DESCRIPTION provided by applicant FINCH is a new imaging technology developed by Celloptic Inc FINCH is the acronym for Fresnel Incoherent Correlation Holography a single beam laserless and motionless holographic principle in which a fluorescent holographic representation of the complete D volume is captured on a digital camera The method obviates the need for serial stacks and captures th ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Augmented Reality System to Teach Hemostatic Agent Use in Hemorrhage Control

    SBC: SimQuest, LLC            Topic: 300

    DESCRIPTION provided by applicant Improvements in pre hospital trauma life support in the past years have led to impressive enhancement in patient survival These achievements have come as the result of improved equipment transport logistics assessment treatment protocols and training of personnel in all levels of the care chain from the point of injury to th hospital One of the areas th ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health

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