Award Data

We propose to employ a novel Boundary Element Method (BEM) numerical technique to develop a parallel computer code that will allow simultaneous solution, in three dimensions (3-D), of the vacuum magnetic vector potential and magnetic field structure for complex geometries. The primary advantages of the chosen approach are the reduction of the dimensionality of the problem from three (volume) to tw ...

DESCRIPTION (provided by applicant): Cardiovascular disease (CVD) is the leading cause of death and the most expensive disease in the U.S. Many patients are asymptomatic before the first serious and often fatal event. Unlike cancers in which numerous under lying pathologies exist, the majority of CVD is caused by atherosclerosis. New solutions for early detection and treatment monitoring of athero ...

This Small Business Innovative Research Phase I research develops technologies to address the increased demands on both families of and institutions serving patients with cognitive and physical impairments to monitor and track patients. Wandering is a common problem in people with dementia. This research expands exisiting system technology to provide monitoring and tracking that covers an area ove ...

DESCRIPTION (provided by applicant): The objective of this project is to develop a new advanced imaging system to allow visualization of small cancerous tumors in situ based on combination of two types of tissue contrast: (1) molecular contrast of deoxygenated hemoglobin associated with the function of aggressive malignancy to develop angiogenesis and consume oxygen and (2) structural contrast ba ...

Many aircraft are hardened against the effects of various forms of various high power electromagnetic waves, including EMP, HPM, and HIRF. These aircraft typically have electrically conductive screens built into their windows, with an electrical connection to the metallic fuselage that forms an electromagnetic seal. To maintain the shielding effectiveness of the window, it is necessary to check pe ...

General Vortex Energy, Inc. (GVE) has designed a flameless/oxidation combustion system for the next generation of propulsion and power generation systems consisting of a two-stage combustor. The flameless/oxidation combustor prototype has been built during Phase I. Combustion in flameless/oxidation mode allow to use: Less amount of air and still have a low emission of NOx, CO, CO2 and low noi ...

The objective of this project is to design and build a seismometer that combines the essential features of a traditional pure analog seismometer, which outputs a voltage signal, with a traditional digitizer, which samples that voltage signal and provides digital word output. The design does not just physically integrate a seismometer with a digitizer. Instead, the design employs a new approach a ...

This phase I proposal addresses ultra-thinning (~ 5-10 micrometer) of Si wafers and memory dies through a mix and match approach in which advanced deep reactive ion etching (DRIE)and pulsed laser etching (PLE)methods are used for coarse and plasmaless XeF2 vapor etching for fine thinning. Die-thinning in sub 10-micrometer regime is a subject of enduring interest in ultra-dense 3D MCM packaging and ...

Presently, scanning and zooming of imaging optics is achieved with bulky mechanical gimbals or using multiple focal plane arrays and associated optics to cover the wide field of view. These approaches are not only expensive in terms of power, size and weight, but also costly. Alternatively, the use of liquid crystal (LC) lenses, LC spatial light modulators and LC scanners in zooming and scanning ...

DESCRIPTION (provided by applicant): We have recently demonstrated marked clinical efficacy in a phase II clinical trial with a peptide vaccine targeting EGFRvIII in newly diagnosed glioblastoma multiforme (GBM) patients. Despite an impressive delay in tim e to progression and 100% increase in survival, these patients nonetheless still succumb to their disease. By studying directly the immune resp ...