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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

Displaying 81 - 90 of 3316 results
  1. Rapid Detection of multiple sepsis pathogens


    Abstract Sepsis is a major public health concern and the primary cause of death in the intensive care unit accounting for more than $ billion of total US hospital costs in Sepsis can lead to a life threatening drop in blood pressure termed septic shock which can quickly lead to the failure of vital organs such as lungs kidneys and liver and eventually to death Nearly all sepsi ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Amyloid Beta Oligomer Induction of Alzheimer's Disease in Nonhuman Primates

    SBC: RXGEN INC            Topic: 100

    PROJECT SUMMARY Patients with Alzheimerandapos s diseaseADsuffer a progressive loss of memory and cognitive abilityand eventual loss of basic bodily functions and deathCurrentlyof Americans overhave AD and its incidence and toll on the healthcare system continues to rise with significant societal impactThere are no treatments for AD to prevent its inexorable courseand a principal obstacle to devel ...

    SBIR Phase I 2017 Department of Health and Human Services
  3. Practical high resolution microscopy of un-cut, un-embedded lung biopsies

    SBC: Applikate Technologies LLC            Topic: NCI

    Project Summary and Relevance The aim of this Phase II SBIR proposal from Applikate TechnologiesLLCis to build on the successful completion of our Phase I milestones with the designconstructionand testing of prototype devices and software for implementing the ClearView tissue histology system in clinical settings by laboratory personnelClearView is a novel approach to performing complete and non d ...

    SBIR Phase II 2017 Department of Health and Human Services
  4. Development of TP for the Induction and Maintenance of Remission in Ulcerative Colitis Patients

    SBC: Thetis Pharmaceuticals LLC            Topic: 300

    ABSTRACT Thetis plans to investigate TP an innovative and potential first in class therapeutic agent as an oral therapy for the induction and maintenance of remission of intestinal inflammation symptoms in ulcerative colitis UC patients While the precise etiology of UC is unknown it is thought to result from an inappropriate inflammatory response to commensal gut bacteria in genetically ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Novel diagnostics for autoimmunity from checkpoint inhibitor immune therapy

    SBC: L2 DIAGNOSTICS, LLC            Topic: NIDDK

    Checkpoint inhibitor CPI therapy has transformed treatment of solid tumors Clinical responses in the range of with prolonged survival have been reported for tumors such as malignant melanoma and non small cell lung cancer that previously had poor response rates and dismal prognoses Current therapies block PD PD L and CTLA and there are other targets being developed such as LA ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Waterproof Leadless Armband For Continuous Wireless Monitoring For Atrial Fibrillation


    PROJECT SUMMARY ABSTRACT No longer than lines of text Atrial Fibrillation AF is the most common sustained dysrhythmia worldwide Although new AF treatment strategies have emerged over the last decade a major challenge facing clinicians and researchers is the paroxysmal often short lived and frequently asymptomatic nature of AF Paroxysmal and asymptomatic AF would be found i ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Interactive Digital Intervention to Prevent Violence among Young Adults

    SBC: Happy People Games, LLC            Topic: NICHD

    Project Summary Abstract Sexual assault SA is prevalent among students at and year colleges The rate of SA among college students is three times greater than the rate in the general population making prevention on college campuses a public health priority There are no college SA prevention programs that document reductions in SA in a rigorous research design Digital applications that us ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Development of a pediatric transcatheter pulmonary valve system

    SBC: Dura LLC            Topic: NHLBI

    DESCRIPTIONprovided by applicantApproximatelybabies in the US and overmillion babies worldwide each year are born with congenital heart defectCHDIt is estimated thatof CHD children have specific heart defects that involve the right ventricular outflow tractRVOTand pulmonary valveThese pediatric patients are typically subjected to multiple invasive open heart surgeries throughout their lifetime in ...

    SBIR Phase II 2017 Department of Health and Human Services
  9. SBIR Phase I: Medical Devices for Real-time Radiation Dosimetry at Sub-millimeter Spatial Resolution

    SBC: eBeam Film LLC            Topic: MI

    This Small Business Innovation Research Phase I project seeks development of a novel dosimeter for 2-D mapping of radiation dose in real-time at sub-millimeter spatial resolution. The high spatial resolution of the dosimeter is essential in supporting stereotactic radiosurgery (SRS) and stereotactic body radiation therapy (SBRT) treatments. These rapidly emerging modalities deliver precise doses o ...

    SBIR Phase I 2017 National Science Foundation
  10. SBIR Phase I: Breathalyzer for Non-invasive Disease Detection Using a Single Ammonia Sensor

    SBC: HEALTH ESENSE, INC.            Topic: BM

    The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project lies in the opportunity to provide accurate, real time information to motivate patients to manage their disease; drive early, evidenced-based interventions; and prevent unnecessary physician visits and hospital stays. This non-invasive device, a breathalyzer, will measure the level of ammonia ...

    SBIR Phase I 2017 National Science Foundation

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