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SBC: Sarcoidosis Diagnostic Testing LLC Topic: NHLBI
DESCRIPTION provided by applicant SARCOIDOSIS DIAGNOSTIC TESTING LLC is a medical diagnostics company developing a diagnostic blood test for sarcoidosis Sarcoidosis is a multisystem granulomatous disorder that affects per people per year in the U S and disproportionately affects African Americans and women Sarcoidosis can lead to advanced pulmonary fibrosis pulmonary hyperte ...STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
Expressing humanized bacterial luciferase in stem cells: Moving beyond firefly luciferase to expand the informational capacity of animal models for regenerative medicineSBC: 490 BIOTECH INC Topic: 200
DESCRIPTION provided by applicant This Small Business Technology Transfer STTR Phase I project proposes to develop autonomously bioluminescent human stem cells for continuous reagent free and real time bioimaging to address the National Institutes of Healthandapos s request for new techniques for non invasive long term tracking of stem cell survivability engraftment and migration followi ...STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
SBC: AGILE HEALTH INC Topic: NIMHD
DESCRIPTION provided by applicant Latinos Kick Buts Mobile Engagement and Cessation Support for Latino Smokers Latinos are less likely than non Hispanic whites to have access to health to have knowledge of existing smoking cessation resources to receive advice to stop smoking and to participate in smoking cessation programs Mobile technologies can dramatically enhance the reach of effectiv ...STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
SBC: KWJ ENGINEERING INC Topic: NIEHS
DESCRIPTION provided by applicant The goal of this STTR Phase I collaboration between KWJ Engineering KWJ and North Carolina State University NCSU will be development of a unique autonomously powered wearable environmental gas sensor for personal exposure monitoring PEM The approach will be to integrate KWJ ultralow power high performance printed amperometric gas sensor for key atmosp ...STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
SBC: Anteana Therapeutics Inc Topic: NIDDK
DESCRIPTION provided by applicant Non steroidal anti inflammatory drugs NSAIDs are among the most widely consumed pharmaceuticals but their prolonged use causes gastric injury and damage to the small intestine Previous work has shown that anandamide an endogenous endocannabinoid substance produced in the gastrointestinal GI mucosa plays an important role in epithelial homeostasis and re ...STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
SBC: PROTEIN METRICS INC Topic: 400
DESCRIPTION provided by applicant Mass spectrometry has become a method of choice for identifying and characterizing small quantities of proteins in complex mixtures However the ability to perform the identification in a high throughput fashion has depended on the availability of high quality protein sequence databases This means that proteins from organisms with unsequenced or poorly sequen ...STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
SBC: BioIncept, LLC Topic: NIAID
DESCRIPTION provided by applicant Recent nuclear accidents and threats have highlighted the growing risk of widespread radiation exposure causing a potentially devastating public health emergency Acute radiation syndrome ARS develops after total body or partial body irradiation at a moderate to high dose and is especially damaging to the immune system Damage to the skin gut and central n ...STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
SBC: LENIMA FIELD DIAGNOSTICS LLC Topic: R
DESCRIPTION provided by applicant Hepatitis B HB and hepatitis C HC are two of the most widespread infections worldwide caused by the blood borne HB virus HBV and HC virus HCV respectively About million and million people suffer from chronic HB CHB and chronic HC CHC respectively while about and people die each year due to the consequence of HB and ...STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
SBC: TRELLIS BIOSCIENCE, INC. Topic: NIAID
DESCRIPTION provided by applicant About of serious bacterial infections are biofilm mediated Not only do biofilms provide an anchor and physical protection for bacterial cells but the physiology and genetic programming of bacteria also shifts between the planktonic free floating and sessile stationary states Most notably antibiotic sensitivity differs betwen the two states with ...STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
Use of EF2K inhibitors to inhibit tumor growth and sensitize cancer cells to existing chemotherapy treatmentSBC: LONGEVICA PHARMACEUTICALS, INC. Topic: 102
DESCRIPTION provided by applicant Eukaryotic elongation factor protein kinase eEF K is a ubiquitously expressed protein that belongs to a family of alpha kinases characterized by an andquot atypicalandquot kinase domain Our recent findings demonstrate that inhibition or genetic inactivation of eEF K protects normal tissues from cytotoxic effects of ionizing radiation and chemotherapeutic ...STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health