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SBC: NEXTRAST, INC Topic: 300
Project SummaryAbstract Our long term goal is to revolutionize the effectiveness of CT imaging for millions of Americans across a broad range of abdominal diseaseDual energy CTDECTprovides powerful clinical diagnostic potential but remains heavily underutilized despite wide scanner availabilityDECT allows materials to be differentiated based on their relative X ray attenuation at low versus high e ...STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
SBC: BARRON ASSOCIATES, INC. Topic: NICHD
DESCRIPTION provided by applicant Obstructive sleep disordered breathing OSDB is common in both children and adults and is recognized as having substantial health related consequences at all ages Laboratory polysomnography PSG is the gold standard for diagnosing OSDB but the procedure is not without problems Polysomnographic studies are complex invasive expensive not universally avail ...STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
SBC: YUMA THERAPEUTICS CORPORAITON Topic: NIA
DESCRIPTION provided by applicant Neurodegeneration in Alzheimerandapos s disease AD may result from deposition of A as plaques in brain tissue However less effort has been made to elucidate the role of tau containing neurofibrillary tangles NFTs in AD Accumulating evidence suggests that tau containing NFTs is an important component in the initiation and progression of AD and other neu ...STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
SBC: AUSCULTECH DX LLC Topic: NHLBI
PROJECT SUMMARY The overall goal of the proposed research and technology transfer effort is to develop a low-cost, point-of-care, mobile device-based technology for automated identification of Stillandapos;s murmur, the most common innocent (benign and harmless) heart murmur of childhood. This novel technology could reduce the current rate of over half a million children unnecessarily referred to ...STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
SBC: EYENUK, INC. Topic: NCATS
DESCRIPTION provided by applicant In this STTR project we present EyeMark a set of advanced image analysis tools for automated computation of biomarkers for diabetic retinopathy DR using retinal fundus images Specifically we will develop tools for computation of microaneurysm MA appearance and disappearance rates jointly known as turnover rates for use as a biomarker in quantifying D ...STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
SBC: CORTICOMETRICS LLC Topic: NIA
Project Summary Normal human neuroanatomy is incredibly variable, and increases with age. This impedes the ability of neuroimaging to detect effects in neurological conditions such as Alzheimerandapos;s disease (AD), Huntingtonandapos;s disease (HD), multiple sclerosis (MS) and schizophrenia. Most of the recently available state-of-the-art quantitative imaging tools still use cross-sectional metho ...STTR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
SBC: KLEIN BUENDEL, INC. Topic: NIA
The United States has the highest rate of incarceration in the world There are over state and federal prisons housing over million prisoners in the United States The demographics of the prison population are shifting Longer sentences and constrained options for early release compound this trend The older adult segment of prison populations has more than tripled since The health ...STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
SBC: POINT DESIGNS, LLC Topic: NICHD
The goal of the proposed project is to develop and commercialize a purely mechanical, ratcheting prosthetic finger – the Point Digit – which 1) has an industry leading strength to weight ratio, 2) can be operated unilaterally (one-handed), 3) offers anatomical rotation and flexion around the patient’s metacarpophalangeal (MCP) joint, and 4) can be custom-made for each patient using advanced ...STTR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
SBC: Brain Solutions, LLC Topic: NIDA
TBDSTTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
SBC: IQ MEDICAL IMAGING LLC Topic: 102
Project SummaryAbstract The neurofibromatosesNFsincluding NFNFand schwannomatosisare a group of autosomal dominant neurogenetic disorders characterized by a predisposition in virtuallyof patients to develop multiple nerve sheath tumorsThe determination of tumor burden on magnetic resonance imagingMRIis indispensable for the longitudinal management of NF patientswhich includes life long follow up f ...STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health