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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Development of an Electromyographically Controlled Electrolarynx Voice Prosthesis

    SBC: GRIFFIN LABORATORIES, INC.            Topic: NIDCD

    DESCRIPTION (provided by applicant): The most common artificial voice source for post-laryngectomy speech rehabilitation is the hand-held buzzer or electrolarynx (EL). This device is relatively easy to use and enables most laryngectomees to verbally communicate, but with reduced intelligibility and markedly degraded naturalness. In addition, EL speech is often described as robotic and monotone, at ...

    STTR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  2. Diabetes Insulin Guidance System to Improve Glycemic Control of Diabetic Patients

    SBC: HYGIEIA RESEARCH, LLC            Topic: NIDDK

    DESCRIPTION (provided by applicant): According to UnitedHealth14 by 2020 half of all Americans would have either diabetes or pre-diabetes with an annual cost of 500 billion - mainly attributed to diabetes related complications. Diabetes is a growing epidemic yet treatment goals are seldom achieved, and patients endure detrimental complications. In the US, 65% of all insulin takers (most of which ...

    STTR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  3. Phase Contrast OCT for Non-Invasive Imaging of Retinovascular Disease

    SBC: VISDEX CORP            Topic: NEI

    DESCRIPTION (provided by applicant): Since its introduction in the 1960's, fluorescein angiography (FA) has been the gold standard for retinal vascular diagnosis. However, FA is costly, invasive, and time-consuming, which limits its usefulness as a screening tool. As a potential non-invasive alternative to FA for diagnosing retinovascular disease, we have developed an imaging method called ph ...

    STTR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  4. Fluorescence Intensity-based Scoring of Macromolecule Crystallization Plates

    SBC: iXpressGenes, Inc.            Topic: NIGMS

    DESCRIPTION (provided by applicant): Crystallization, followed by subsequent structure determination, is a major step in understanding the structure- function relationship of macromolecules. Understanding macromolecule structure has become a key part in the development of new pharmaceuticals, and is a major area of NIH research. Crystallization however is also the rate limiting step, despite techn ...

    STTR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  5. Development of an automated noninvasive system for sleep restriction in rodents

    SBC: AFASCI, INC.            Topic: NHLBI

    DESCRIPTION (provided by applicant): Sleep deprivation (SD) occurs universally in modern societies and causes significant social and financial harm. Numerous human and animal studies indicate that various forms of SD are deleterious to mental and physicalhealth. Therefore, SD has been recognized as an unmet challenge to public health. There is increased need to study the effects of different forms ...

    STTR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  6. Optogenetic Multiparametric Assay for HT Cardiotoxicity Testing

    SBC: VALA SCIENCES, INC.            Topic: NHLBI

    DESCRIPTION (provided by applicant): Monitoring physiology of individual cardiomyocytes in high throughput has not been reported. The inability to perform high throughput physiological measurements limits many basic and applied studies, including the use of stem cell derived cardiomycoytes in cardiotoxicity testing. Current automated cardiotoxicity tests have poor predictive value because they use ...

    STTR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  7. Development of flow and vascular quantification software for the assessment of MR

    SBC: Magnetic Resonance Innovations, Inc.            Topic: NHLBI

    DESCRIPTION (provided by applicant): There has been a huge increase in demand for comprehensive quantitative analysis of neurovascular imaging data produced in the clinical setting for diseases such as multiple sclerosis, traumatic brain injury, stroke anddementia. Our objective in this project is to design and develop advanced image processing software that can rapidly and accurately analyze such ...

    STTR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  8. The Bumps ad device for rapid non invasive quantification of touch sensation

    SBC: Neuro Devices, Inc.            Topic: NCATS

    DESCRIPTION (provided by applicant): Our proposal describes an elegant device called the Bumps that quantifies touch sensation on the fingers at low micron levels. The objectives are to diagnose peripheral neuropathy near its onset, when the possibility for reversal is highest, and to monitor either progression or reversal of neuropathy during treatment. Target neuropathies are those related to ch ...

    STTR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  9. A simple ventricular assist device for short term cardiac support

    SBC: MICHIGAN CRITICAL CARE CONSULTANTS, INC.            Topic: NHLBI

    DESCRIPTION (provided by applicant): Cardiogenic shock can occur after open heart surgery or in association with myocardial infarctions, and carries a high mortality. Initiation of mechanical circulatory support can restore blood flow to vital organs and potentially save lives. In this proposal, we plan to develop a device designed to provide temporary mechanical circulatory support which is super ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  10. Development of a Perfusion-induced Systemic Hyperthermia Delivery Apparatus

    SBC: MICHIGAN CRITICAL CARE CONSULTANTS, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): Lung cancer is the leading cause of cancer-related deaths in men and women. The prognosis for patients with advanced stage non-small cell lung cancer (NSCLC), which accounts for 75% of all new lung cancer cases, is dismal with currently available chemotherapy regimens providing only a 9-12 month median survival. Thus, our long term goal is to develop a more eff ...

    STTR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
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