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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Resonant-Photonic-Device-Enhanced SERS Substrate with Pinpointed Plasmonic-Active

    SBC: OMEGA OPTICS, INC.            Topic: NIEHS

    DESCRIPTION (provided by applicant): The use of Surface Enhanced Raman Scattering (SERS) for biomolecule detection has been restricted due to the great difficulty of fabricating ultrasensitive and reproducible surface-plasmonic-resonance (SPR) substrates.Therefore, detecting extremely small amount of biomolecules for clinical application is significantly limited. In this STTR Phase II research, w ...

    STTR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  2. Alafair Biosciences develops cross-linked polysaccharide hydrogel films to addres

    SBC: ALAFAIR BIOSCIENCES, INC.            Topic: NIGMS

    DESCRIPTION (provided by applicant): The goal of this STTR project is to develop a pre-formed, naturally-based hydrogel postoperative adhesion barrier with improved handling characteristics, laparoscopic deliverability, and consistent efficacy. Our technology is based on a novel, patented process that imparts exceptional elasticity and toughness on normally brittle, weak materials. Postoperative a ...

    STTR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  3. IYG-Family: Beyond the talk to effective pregnancy, STI, and HIV prevention

    SBC: Radiant Creative Group, LLC            Topic: NICHD

    DESCRIPTION (provided by applicant): The goal of this 3 year Fast-Track STTR is to develop and evaluate a home-based intervention ('it's Your Game- Family') to provide age-appropriate sexual health life skills education and training for children (11-14 years) and to enhance parents' skills and self-confidence in support of this training. IYG-Family (IYG-F) will be an on-line g ...

    STTR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  4. Development of a Biochemical Diagnosis for Creutzfeldt-Jakob disease

    SBC: Amprion, Inc.            Topic: NINDS

    DESCRIPTION (provided by applicant): Human prion diseases are infectious and invariably fatal forms of neurodegenerative diseases, including sporadic Creutzfeldt-Jakob disease (sCJD), the most common form, and variant CJD (vCJD) which is associated to consumption of cattle meat infected by bovine spongiform encephalopathy. Currently there is not sensitive, objective and non-invasive biochemical di ...

    STTR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  5. rAAV5-hCNGB3 Gene Therapy for Achromatopsia: Safety and Efficacy in a Dog Model

    SBC: APPLIED GENETIC TECHNOLOGIES CORPORATION            Topic: N

    DESCRIPTION provided by applicant Complete achromatopsia is an autosomal recessive inherited congenital disorder of retinal cone photoreceptors Patients with complete achromatopsia experience extreme light sensitivity and daytime blindness and best visual acuity under non bright light conditions is usually or worse and generally stable over time In addition to poor acuity hypersensit ...

    STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  6. Position tracking and mobility assessment system for indoor monitoring of elders

    SBC: EMBEDRF LLC            Topic: NIA

    DESCRIPTION (provided by applicant): The long term objective of this project is to enable elderly persons to independently live within their own homes later into their lives with the assurance that their safety and well-being can be remotely monitored by health care professionals. A critical component of remote health care monitoring is physically tracking the location of the patient within a livi ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  7. Development of monoclonal catalytic antibodies for HIV immunotherapy

    SBC: COVALENT IMMUNOLOGY PRODUCTS, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): We have raised murine monoclonal antibodies (MAbs) to a conserved region of the CD4 binding site of gp120 (CD4bs) that neutralize genetically diverse HIV strains. The MAbs have a novel mechanism of action. They hydrolyze multiple molecules of gp120, thereby imparting MAb increased biological efficacy. About 10% of HIV infected subjects develop resistance to cur ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  8. Cotton Rat: Animal Model Predictive of Clinical Responses to HSV Vaccines

    SBC: VIRION SYSTEMS, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): Genital herpes is one of the most prevalent sexually transmitted infections worldwide and is associated with substantial morbidity. The impact of genital herpes as a public health threat is amplified because of its epidemiologic synergy with HIV. Epidemiological studies consistently demonstrate that HSV infection increases the risk of HIV transmission and acqu ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  9. A cost-effective bioreactor to advance functional tissue engineering of cartilage

    SBC: Apex Biomedical Company, LLC            Topic: NIAMS

    DESCRIPTION (provided by applicant): Osteoarthritis (OA) is the leading cause of chronic disability in the United States. A clinical goal in the treatment and prevention of OA is to develop replacement cartilage using tissue engineering (TE) technologies. Although TE cartilage presently lacks the mechanical stability of native cartilage, studies have demonstrated that mechanical stability can be e ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  10. Early detection of prostate cancer in urine

    SBC: New Horizons Diagnostics            Topic: NCI

    DESCRIPTION (provided by applicant): Prostate cancer is the second most common cancer in men, and the second leading cause of cancer death. However, when prostate cancer is diagnosed in its early stages, it can be effectively treated and cured. Combined with the digital rectal examination, the prostate specific antigen (PSA) test has been widely used to detect prostate cancer in its early stages. ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
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