Award Data

The feasibility for fusion as a practical energy source needs to be enhanced significantly by removing some of the restrictions that low-temperature superconductors put on the fusion magnet systems. This can be done by using high-temperature superconductors, allowing for much larger temperature margins, a higher magnet performance and less mechanical degradation during operation. There are curren ...

This Small Business Innovation Research (SBIR) Phase I project seeks to address the unmet need for high-throughput, cost-effective research tools to model the metastasis of cancer cells. The proposed research objectives are to (1) discover cost-effective, commercially scalable methods allowing the production of aligned nanofibers in a 96-well plate format and (2) verify that the fiber alignment is ...

DESCRIPTION (provided by applicant): Preeclampsia, a hypertensive disorder of pregnancy, is a leading cause of maternal and neonatal morbidity and mortality around the world, responsible for approximately 76,000 maternal and 500,000 infant deaths per year.As a heterogeneous and poorly understood disorder, its pathogenesis and possible treatments are an area of active research. While the majority o ...

DESCRIPTION (provided by applicant): The broad objective of this proposal is to improve the clinical effectiveness of liver lesion biopsy by fusing respiratory-compensated PET with CT images in the CT suite. On CT imaging alone, localization of liver lesions can potentially be challenging, particularly in selected cases where differentiation of the tumor from adjacent liver parenchyma may be diffi ...

DESCRIPTION (provided by applicant): Validation of computing algorithms has been a challenging topic over the last few years. In fact, several international workshops in the medical imaging field started to involve the community through grand challenges . A grand challenge involves selecting driving biological/scientific problem and asking experts to submit their best results and methods to solve ...

DESCRIPTION (provided by applicant): Image-based evaluation of pathologies over time is complicated by variability in image acquisition and patient positioning, deformations due to respiratory and cardiac motion, and the clinical standard in radiology of comparing unaligned images. This application proposes a computational method for longitudinal image analysis that captures, illustrates and quant ...

DESCRIPTION (provided by applicant): Nearly 1.7 million Americans suffer traumatic brain injury (TBI) annually, which constitutes an important and significant US medical health concern. Although neuroimaging plays an important role in pathology localization and surgical planning, TBI clinical care does not currently take full advantage of neuroimaging computational technology. We propose to develo ...

The objectives of this Phase-II research effort is focused on transitioning noninvasive diagnostic techniques based on ultrafast lasers for characterizing nanoenergetic materials and their performance in rocket engine environments. Through the use of ultrafast laser imaging and spectroscopy, it is possible to isolate and characterize each physical process from initiation through energy release an ...

Redox flow batteries are a promising technology for electrical energy storage for renewable energy sources; however traditional redox flow batteries are limited in their use due to non-uniform pressure drops and mass transfer limitations, as well as high manufacturing costs related to the felt material costs for the electrode and component alignment challenges during manufacturing.General Statemen ...

DESCRIPTION (provided by applicant): Enabling high dose regional chemotherapy with minimal systemic toxicity Abstract: The primary objective of this proposed study is to develop a filtration system that maximizes the removal (gt90%) of chemotherapeutic agents, such as doxorubicin, from blood while minimizing adverse effects of filtration on blood chemistry and hematological parameters. Vascular V ...