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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Development of mitochondrial disease mouse models

    SBC: B-MoGen Biotechnologies Inc            Topic: OD

    Project Abstract Mitochondria are double membrane bound organelles that are found in all eukaryotic cells and carry a specialized circularkb genomeThere is a group of devastating human genetic diseases caused by inherited or spontaneous mutation of genes encoded within the mitochondrial genomeThese diseases can cause a wide array of medical problems from subtle muscular weakness to extreme neuromu ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  2. Hybrid DNN-based Transfer Learning and CNN-based Supervised Learning for Object Recognition in Multi-modal Infrared Imagery

    SBC: TOYON RESEARCH CORPORATION            Topic: 1

    On this effort Toyon Research Corp. and The Pennsylvania State University are developing deep learning-based algorithms for object recognition and new class discovery in look-down infrared (IR) imagery. Our approach involves the development of a hybrid classifier that exploits both transfer learning and semi-supervised paradigms in order to maintain good generalization accuracy, especially when li ...

    STTR Phase I 2018 Department of DefenseNational Geospatial-Intelligence Agency
  3. Algorithms for Look-down Infrared Target Exploitation

    SBC: SIGNATURE RESEARCH, INC.            Topic: 1

    Signature Research, Inc. (SGR) and Michigan Technological University (MTU) propose a Phase I STTR effort to develop a learning algorithm which exploits the spatio-spectral characteristics inherent within IR imagery and motion imagery.Our archive of modelled and labeled data sets will allow our team to thoroughly capture the variable elements that will drive machine learning performance.The overall ...

    STTR Phase I 2018 Department of DefenseNational Geospatial-Intelligence Agency
  4. Peripheral FAAH inhibitor, URB937, as an opioid-sparing analgesic for chronic pain.

    SBC: ASPIREBIO CORP            Topic: 101

    PROJECT SUMMARY Opioid drugs are powerful analgesicsbut their side effect profile strongly limits their useIndeedtheir addictive properties have led to an epidemic of abuse in the US that accounts forof the global utilization of prescription opioid analgesics in the USwith a market of over $billion per yearPrevious studies have shown that the endocannabinoid neurotransmitteranandamidecontrols noci ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  5. Astroglial EAAT2 Changes in Live TBI Brain Determined by PET Imaging

    SBC: RIO PHARMACEUTICALS, INC.            Topic: NINDS

    PROJECT SUMMARYTraumatic Brain InjuryTBIis one of the most significant Public Health trauma diseases of our timeDiagnoses of various TBI forms rely on patient self reportingestablished clinical rating scalesand multimodality imaging to an extentTBI elicits complexheterogeneous pathological eventsincluding mechanical injuryhemorrhageand progressive secondary processes such as central and peripheral ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  6. Magnetic camera based on optical magnetometer for neuroscience research

    SBC: FieldLine Inc.            Topic: 101

    Abstract During Phase Iwe will test the feasibility of developing a magnetographic camera technology as a new tool in neuroscience to facilitate the detailed analysis of electrical currents in diverse neuronal circuitsInstead of photographic imagesthe camera will produce single shot images of the magnetic fields from in vivo samples of interestsuch as a patch of the grey matter in the cerebral cor ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  7. Cuff Electrodes with Soft Wire Electrical Leads

    SBC: TDA RESEARCH, INC.            Topic: 102

    Project Summary AbstractDevelopment of a Nerve Cuff Electrode from Soft and Elastomeric Conducting Wires STTR Phase I ApplicationPIBrady ClapsaddleTDA ResearchIncBio electronic interfaces are used in a wide array of applications for recording and providing electrical impulses to treat diseaseOne common interface device for the PNS is the cuff electrodeCurrent cuff electrodes have many failure mode ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  8. A user-friendly microfluidic chip for anti-epileptogenic drug screening

    SBC: Xona Microfluidics, Inc.            Topic: 101

    New pharmacological treatments for epilepsy will be discovered through the development of new screening platforms that are rapidreliableand can identify novel disease modifying therapiesor anti epileptogenic treatmentsXona MicrofluidicLLCXonais in a unique position to provide such screening tools and services for epilepsy researchXona focuses on the development of microfluidic platforms for neuron ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  9. Sonomyographic Control of Fiber-Optically Sensorized Prosthetic Fingers for Graded Force Actuation

    SBC: INTELLIGENT FIBER OPTIC SYSTEMS CORP            Topic: NINDS

    Sonomyographic Control of Fiber Optically Sensorized Prosthetic Fingers for Graded Force Actuation Intelligent Fiber Optic Systems CorporationIFOSCalle del MundoSanta ClaraCAwww ifos com PROJECT SUMMARY ABSTRACTMAXIMUMLINESIn this Phase I SBIR applicationIFOS and George Mason UniversityGMUpropose an innovative control system leveraging on two emerging technologiesultrasonic imaging based readout o ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  10. Development of a low cost point-of-care device for rapid pathogen detection

    SBC: ELECTRONUCLEICS INC            Topic: NIAID

    Project Summary This project is focused on feasibility testing of a new device based on electromechanical signal transduction for the low cost$in electronicsoptics free and amplification freee gno PCRdetection of DNA RNA at ultralow concentrationThe device addresses the projected $B disease diagnostics market and is well suited for the detection of bacterial pathogens in body fluidsfood and water ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
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