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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 91 - 100 of 207728 results
  1. Neurosessments: Developing a quick, objective motor test to prompt cognitivetesting in primary care

    SBC: NEUROSESSMENTS LLC            Topic: NIA

    PROJECT SUMMARY/ABSTRACT Alzheimer’s disease (AD) is the leading cause of dementia in the United States, affecting one out of every nine older adults. However, Alzheimer’s disease and related dementias (AD/ADRD) can be difficult to diagnose, with physicians missing nearly half of all probable dementia cases. Rates of missed diagnosis are even higher among Black older adults. The majority of ph ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  2. Using Machine Learning and Blockchain Technology to Reduce Drug Diversion in Hospitals

    SBC: AUTONOMOUS HEALTHCARE INC            Topic: NIDA

    Based on an analysis, the volume of dosage lost due to diversion increased from 21 million in 2017 to 47 million in 2018, a 126% increase. Addressing the drug diversion problem is a multi-faceted problem involving many components ranging from provider training to implementation of hardware and software systems to manage access to controlled substances. However, despite recent improvements in contr ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  3. PET Imaging to Evaluate a Novel Chemokine Antagonist to Protect Synapses in ADRD

    SBC: CREATIVE BIO-PEPTIDES INC            Topic: NIA

    7. Project Summary ADRD dementias account for up to 25% of all dementias in patients older than 65 years and there is strong evidence of co-morbid pathologies caused by (amyloid β (Aβ), tau and α-synuclein (αSyn). The degree of AD- related pathology in Lewy Body Dementias (LBD) is moderate or severe in 50% of PDD and more than 70% of DLB patients have concomitant AD-related pathology so that t ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  4. Novel Extracorporeal Device 'Amytrapper' To Remove Beta Amyloid In Alzheimer'sDisease

    SBC: Recombinant Technologies LLC            Topic: NIA

    Abstract Alzheimer’s disease is the most common cause of dementia and fourth most common cause of death. Amyloid-beta (Aβ) plays a crucial role in initiation and progression of Alzheimer’s disease (AD). Removal of circulating Aβ would shift the equilibrium in Aβ levels between brain and blood towards blood. This shift would deplete brain amyloid levels and improve memory. Three commercial m ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  5. ETAware: Continuous monitoring of the functional impact of essential tremor

    SBC: Great Lakes Neurotechnologies Inc.            Topic: NIA

    SummaryThe objective is to design and clinically assess ETAware, an adaptive, wearable system to monitor the impact of tremor on activities of daily living (ADL) for the evaluation and optimization of therapeutic interventions in patients with essential tremor (ET) as there is currently no technology that can assess the functional impact of tremor on ADL. ETAware will focus on ET, the most common ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  6. Assessment Validation

    SBC: NEUROCOMP SYSTEMS            Topic: NIA

    Numerous exploratory research studies over the past decade have demonstrated good to excellent agreement of remote neurocognitive assessment (rNCA) compared to paper-based Face-to-Face (p-FTF) by both televideo and telephonic modalities. Studies in samples of elderly subjects with Alzheimer’s disease and related dementias reported similar results. Rationale for rNCA include addressing the needs ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  7. Cue-induced drug craving monitoring for opioid use disorder with visual evoked potentials

    SBC: NEUROTYPE INC.            Topic: NIDA

    Project Summary / Abstract More than 2 million people in the United States have an Opioid Use Disorder (OUD). Overall, at least half of the treatment-seeking population relapse, contributing to over 75,000 overdose deaths annually. The purpose of this SBIR Fast-Track application is to create a regulated device to objectively monitor Cue-Induced Craving (CIC) in Opioid Use Disorder (OUD) patients. ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  8. Development of an Oscillated Insertion tool to Eliminate Surgically Induced Neurodegeneration for Optical Neuroimaging of Cognitive Aging and Dementia

    SBC: ACTUATED MEDICAL, INC.            Topic: NIA

    This Phase I SBIR develops a system for gentle and accurate insertion of large optical neuroscience probes (e.g., GRIN lenses) to improve outcomes in aging research. Additionally, the project supports Qingguang Zhang. Ph.D. through the NIA Research and Entrepreneurial Development Immersion (REDI) program at a small business. Entrepreneurial development activities for his project will include proje ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  9. Modular Virtual Reality Therapeutic for Opioid and Stimulant Use Disorders

    SBC: INNATEVR LLC            Topic: NIDA

    PROJECT SUMMARY Opioid and/or Stimulant Use Disorders (OUD/StUD) are chronic, recurring conditions that if left untreated, pose a significant and ongoing public health and safety threat, with costs associated with OUD alone in the US exceeding one trillion dollars annually. Virtual Reality Cue Exposure (VRCE) employs safe and controlled repeated exposure to a variety of substance use cues and envi ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  10. Commercialization of an Improved Treatment of Extremity Fractures Using a Regenerative Bone Adhesive to Accelerate Bone Healing in Aging Patients

    SBC: REVBIO, INC.            Topic: NIA

    Project Abstract/Summary In the U.S., about 2.1 million people experience a fragility fracture each year. This number is expected to double or triple by 2040 as the population ages. Injuries in the upper and lower extremities equate to more than 40% of fragility fractures, and experiencing a prior fracture is associated with an 86% increased risk of recurrence. Falls from standing height and other ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
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