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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

Displaying 1 - 10 of 166591 results
  1. Validation of a Performance Based Measure of Functioning in MCI and Early AD

    SBC: NEUROCOG TRIALS            Topic: NIA

    Project Summary Alzheimer s disease AD is expected to rise in prevalence from to million Americans by leading to of deaths among adults over This epidemic is projected to overwhelm healthcare and economic resources with costs reaching $ billion in the US in and $ trillion by There is no cure for AD and no new drugs have been successful in treating the advance ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  2. Minimally Invasive Cardiac Sympathetic Denervation for Malignant Ventricular Arrhythmia

    SBC: Coridea, LLC            Topic: NHLBI

    Sympathetic innervation of the heart plays a critical role in arrhythmogenesis and recent studies have highlighted the role of surgical sympathetic denervation in management of refractory ventricular arrhythmias The procedure although safe is very invasive and performed via thoracoscopy using single lung ventilation This is not tolerated by patients with lung disease or severe structural heart d ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  3. Optical Dosimeter guided Photodynamic Therapy

    SBC: Physical Sciences Inc.            Topic: 102

    Photodynamic Therapy PDT is a promising modality for cancer treatment Oxygen molecules in the metastable singlet delta state O are believed to be the species that destroys cancerous cells during PDT Despite the benefit of targeted PDT that kills tumors selectively with minimum effect on surrounding healthy tissues at the present time it is difficult if not impossible to predict the res ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  4. Noninvasive urinary monitoring of NASH by activity based nanosensors

    SBC: Glympse Bio, Inc.            Topic: 300

    Project Summary Abstract Nonalcoholic steatohepatitis NASH is dubbed the stealth epidemic and in the U S alone percent of the million people who are estimated to have NASH will progress and develop life threatening conditions including fibrosis cirrhosis hepatocellular carcinoma and liver failure By the year NASH is projected to be the leading indication for liver transplanta ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  5. MUC assay for the early diagnosis and management of benign and malignant pancreatic diseases

    SBC: Sanguine Diagnostics And Therapeutics, Inc.            Topic: 300

    Abstract The goal of this Fast track application is to develop a non invasive diagnostic test based on MUC and MUC mucins that can serve as an adjunct to cytological analysis of fine needle aspirates FNAs for accurate prediction of malignancy in patients with cystic pancreatic lesions Due to asymptomatic nature and lack of methods for early detection andgt of pancreatic cancer PC p ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  6. Development of Novel and Affordable Neoglycosylated Long Acting Superactive Analog of Human FSH for Infertility

    SBC: TROPHOGEN INC            Topic: NICHD

    PROJECT SUMMARY ABSTRACT It is estimated that over of all American couples suffer from infertility a topic of great importance to NICHD and cited frequently by this Institute Professional American women andamp those from all developed nations increasingly delay childbearing for several years compared to the past because of career advancement and increasing social acceptability This problem ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  7. Inspiration Point A Digital Pulmonary Rehabilitation Tool for use with Self Management Interventions

    SBC: BLUE MARBLE REHAB INC.            Topic: NHLBI

    Project Summary The broad long term objective of this Fast Track proposal is to develop an innovative self management intervention SMI technology Inspiration Point for the treatment and study of Chronic Obstructive Pulmonary Disease COPD This application directly addresses the NHLBI SBIR requests for proposals for the development of innovative technologies for COPD the development of techn ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  8. High Density Miniaturized Zero Switching Stimulation and Recording Headstage for Small Animals

    SBC: ADVANCED MEDICAL ELECTRONICS CORPORATION            Topic: 101

    Project Summary Abstract Combining high channel count electrophysiological recording of neural activity with patterned electrical micro stimulation has been severely constrained by technical limitations Foremost among these limitations are the problems associated with simultaneous recording and micro stimulation Stimulation artifacts are up to four orders of magnitude larger than the neural sig ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  9. Long non coding RNA signatures to distinguish fibromyalgia syndrome from rheumatic diseases

    SBC: IQUITY LABS, INC.            Topic: NIAID

    No other group of diseases encompasses a greater pathophysiology than do the rheumatic diseases Spanning multiple organ systems clinical decisions often rely on coordinated efforts from primary care providers and rheumatologists to rule in or rule out differential diagnoses when treating inflammatory conditions such as rheumatoid arthritis RA and systemic lupus erythematosus SLE RA is a sym ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  10. The Oaks A Mobile Exercise and Education Program for People with Osteoarthritis of the Knee

    SBC: BLUE MARBLE REHAB INC.            Topic: NIA

    Project Summary This Fast Track SBIR project long term objective is to develop and test of a minimum viable product MVP of The Oaks a perioperative digital education assessment and guided exercise software application for adults with osteoarthritis of the knee KOA awaiting total knee replacement TKR surgery This product is relevant to the mission of the NIA because it addresses the call ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health

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