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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

Displaying 1 - 10 of 164378 results
  1. Retrofittable and Transparent Super-Insulator for Single-Pane Windows

    SBC: NanoSD, Inc.            Topic: DE-FOA-0001429

    NanoSD, Inc. with its partners will develop a transparent, nanostructured thermally insulating film that can be applied to existing single-pane windows to reduce heat loss. To produce the nanostructured film, the team will create hollow ceramic or polymer nanobubbles and consolidate them into a dense lattice structure using heat and compression. Because it is mostly air, the resulting nanobubble s ...

    SBIR Phase I 2016 Department of Energy
  2. Retrofittable and Transparent Super-Insulator for Single-Pane Windows

    SBC: NanoSD, Inc.            Topic: DE-FOA-0001429

    NanoSD, Inc. with its partners will develop a transparent, nanostructured thermally insulating film that can be applied to existing single-pane windows to reduce heat loss. To produce the nanostructured film, the team will create hollow ceramic or polymer nanobubbles and consolidate them into a dense lattice structure using heat and compression. Because it is mostly air, the resulting nanobubble s ...

    SBIR Phase II 2016 Department of Energy
  3. Hyperphosphorylated tau aggregation kit to identify tauopathy risk factor

    SBC: CAYMAN CHEMICAL COMPANY, INC.            Topic: NIA

    PROJECT SUMMARY Millions of Americans are suffering from the devastation of cognition decline and other neurological dysfunctions due to one of the neurodegenerative diseases of tauopathy Some of the prominent tauopathies include Alzheimer s disease Pick s disease traumatic brain injury and chronic encephalopathy There is no cure for any of the tauopathies and the actual cause or exogenous r ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. A Novel Strategy to Identify Substances that Improve Mitochnodrial Fitness

    SBC: CYTEGEN CORPORATION            Topic: NIA

    Project Summary Abstract Mitochondrial dysfunction causes mitochondrial diseases and is tightly linked to aging and neurodegenerative disorders such as Parkinsonandapos s and Alzheimerandapos s Recent discoveries support that mitochondrial dysfunction can be overcome to treat age related decline Cytegenandapos s hypothesis is that exercise induces the secretion of blood borne proteins that act ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Developing an automated yeast dissection system for aging research

    SBC: INNOVATIVE BIOCHIPS, LLC            Topic: NIA

    Project Summary Developing an Automated Yeast Dissection System for Aging Research Aging is the single greatest risk factor for diseases that are principal causes of mortality The objectives of aging research are to discover key genes and pathways related to aging that may eventually contribute to retardation of aging and a delay in the onset of age associated diseases The budding yeast Sacchar ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Mitochondrial Targeted Nano-antioxidants to Treat Alzheimer's Disease

    SBC: ACELEROX, LLC            Topic: NIA

    ABSTRACT PROJECT SUMMARY Alzheimer s disease AD is characterized by hyperphosphorylated tau protein which causes impaired axonal transport in neurons In recent years multiple researchers have determined that oxidative stress appears to be a significant early event in the pathogenesis of AD in preclinical AD models and in AD patients We have shown that reducing oxidative stress through quench ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Telehealth Intervention for Improved Blood Pressure Control with Targeted Incentives: Using New Technologies and Insights From Behavioral Economics to Increase the Effectiveness of Behavioral Change

    SBC: WELLTH, INC.            Topic: NIA

    PROJECT SUMMARY ABSTRACT Hypertension or sustained systolic and diastolic blood pressure BP of and mm Hg or higher is among the most frequently encountered conditions in primary care in the U S The estimated prevalence is among all U S adults and increases with age to affect of seniors Hypertension is also the leading risk factor for cardiovascular disease global mortality ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Self-crosslinkable hydrogel as an embolic agent for traumatic hemorrhage control

    SBC: EMBOMEDICS, INC.            Topic: 300

    ABSTRACT Trauma is the th leading cause of morbidity and mortality after heart disease malignancies and lower respiratory illnesses in the United States Blunt abdominal trauma BAT is commonly caused by vehicular accidents and falls Uncontrolled bleeding is a major factor in early mortality after trauma contributing to to of trauma related deaths Transcatheter arterial embolization ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Biocatalytic production of precursors to lutein and zeaxanthin to address age-related macular degeneration

    SBC: ESCAZYME BIOCHEMICALS, LLC            Topic: N

    Project Summary Atrophic dry age related macular degeneration AMD is the leading cause of severe loss of vision for those over age Dietary supplements containing lutein and zeaxanthin are recommended by the NEI for those at risk of late AMD There has been a corresponding growth in demand for these two xanthophylls Lutein and zeaxanthin are currently sourced from marigolds grown mostl ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Breakthrough sub-cellular 3D chemical composition research platform for live cells, based on the new invention of nanoscale- confocal photothermal IR micro-spectroscopy (n-CPIR)

    SBC: ANASYS INSTRUMENTS CORPORATION            Topic: 100

    Abstract This proposal will lead to a Breakthrough sub cellular D chemical composition research platform for live cells based on the new invention of sub micron confocal photothermal IR micro spectroscopy CPIR Label free sub micron chemical imaging and spectroscopy has long been sought for visualization of biomolecules and materials in complex living systems Many diseases first manifest ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health

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