THE PURPOSE OF THIS GRANT IS TO SELECT APPROVABLE DRUGS FOR THE TREATMENT OF FOUR ORPHAN DISEASES: SICKLE CELL DISEASE,THALASSEMIA, HEMOCHROMATOSIS, AND ERYTHROPOIETIC PORPHYRIAS.

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: N/A
Agency Tracking Number: 470
Amount: $56,000.00
Phase: Phase I
Program: SBIR
Awards Year: 1983
Solicitation Year: N/A
Solicitation Topic Code: N/A
Solicitation Number: N/A
Small Business Information
Atmospheric Health Sciences
152 Parsonage Hill Road, P.o. Box 307, Short Hills, NJ, 07078
DUNS: N/A
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 DOMINGO M. AVIADO
 PRINCIPAL INVESTIGATOR
 (201) 379-3141
Business Contact
Phone: () -
Research Institution
N/A
Abstract
THE PURPOSE OF THIS GRANT IS TO SELECT APPROVABLE DRUGS FOR THE TREATMENT OF FOUR ORPHAN DISEASES: SICKLE CELL DISEASE,THALASSEMIA, HEMOCHROMATOSIS, AND ERYTHROPOIETIC PORPHYRIAS.FROM THE AVAILABLE WORLD MEDICAL LITERATURE ON THE FOUR DISEASES, DRUGS THAT ARE CLAIMED TO BE EFFECTIVE WILL BE EVALUATED AND CATEGORIZED AS TO THE EXTENT OF CLINICAL TESTING AND ANIMAL EXPERIMENTATION. THE THERAPEUTIC REVIEWS WILL BE EXAMINED BY A GROUP OF CONSULTANTS WHO WILL IN TURN SELECT APPROVABLE DRUGS FOR SUBMISSION TO THE ORPHAN PRODUCTS BOARD. PROMISING DRUGS THAT NEED ADDITIONALBUT MINIMAL RESEARCH WILL BE SELECTED FOR PHASE II STUDIES ON ANIMALS AND PATIENTS. IT IS EXPECTED THAT THIS PROJECT WILL HASTEN THE SELECTION PROCESS AND COMMERCIAL INTRODUCTION OF DRUGS FOR ORPHAN DISEASES IN GENERAL, PARTICULARLY OF HEREDITARY ERYTHROCYTIC DISEASES.

* information listed above is at the time of submission.

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