Agent Defeat Short Term Neutralization Data Colloction and Modeling

Award Information
Agency: Department of Defense
Branch: Air Force
Contract: F08630-03-C-0018
Agency Tracking Number: 021MN-0573
Amount: $736,335.00
Phase: Phase II
Program: SBIR
Awards Year: 2003
Solicitation Year: N/A
Solicitation Topic Code: N/A
Solicitation Number: N/A
Small Business Information
AUBURN CHEMICAL CO., INC.
2058 Fieldview Drive, Auburn, AL, 36832
DUNS: 944679836
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Betty Neely
 President
 (334) 826-6500
 B.T.Neely@auburnchemical.com
Business Contact
 Betty Neely
Title: President
Phone: (334) 826-6500
Email: B.T.Neely@auburnchemical.com
Research Institution
N/A
Abstract
This research will determine extent and nature of the neutralization of bacterial spores when they are exposed, for very short times to high temperatures, pressures, and chemicals important in Agent Defeat weapons.. An exposure system will be constructedcapable of providing the ultra-short exposure times (on the order of ms) that are characteristic of bomb explosions and will be capable of exposing bacterial spores to temperatures up to 1,200 K and to pressures up to 5 bar. Modeling of the flows will beused to specify an array of tube dimensions and applied pressures to achieve the desired set of reaction conditions. The sample injection system will ensure rapid and uniform injection of spores without exposing them to high temperatures prior toinjection. Collection will utilize a design that will ensure efficient collection with rapid cooling of collected samples. The test biological threat agent simulant will be spores of Bacillus thuringiensis (Bt).The extent of neutralization will beevaluated on the basis of change in viability using conventional microbiological assay as well as from methods designed to rescue damaged, but not killed, spores. In addition, the mechanisms by which inactivation occurs will be sought using specialbiochemical analyses.

* information listed above is at the time of submission.

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