Neuromonitoring of Traumatic Brain/blast Injury

Award Information
Agency:
Department of Defense
Branch
Office of the Secretary of Defense
Amount:
$99,973.00
Award Year:
2010
Program:
SBIR
Phase:
Phase I
Contract:
W81XWH-10-C-0061
Award Id:
96844
Agency Tracking Number:
O093-H06-3094
Solicitation Year:
n/a
Solicitation Topic Code:
OSD 09-H06
Solicitation Number:
n/a
Small Business Information
2237 Faraday Ave, Suite 100, Carlsbad, CA, 92008
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
969842715
Principal Investigator:
DjordjePopovic
Director of Research
(760) 720-0099
dpopovic@b-alert.com
Business Contact:
ChristineBerka
Chief Executive Officer
(760) 720-0099
chris@b-alert.com
Research Institute:
n/a
Abstract
It is well known that the brain is the organ most sensitive to ischemia/hypoxia. Noninvasive continuous monitoring of cerebral blood flow autoregulation, cerebrovascular reactivity and related phenomena such as cerebral vasospams in combat casualties could guide clinicians/medics in adjusting the strategy of resuscitation and acute care, and therefore contribute to a substantially improved survival and functional outcome. We propose to develop a small, light-weight, battery powered and hand-portable 3-channel monitor that combines electro- and rheoencephalography (EEG and REG). While REG detects changes in cerebral vascular bed, EEG can be used to detect post-traumatic non-convulsive seizures or reversible breakdown of the synaptic transmission. The monitor consists of a smaller (2 x 2 x 0.5 in) wearable unit for data acquisition and a larger (7 x 5 x 0.8) unit for visualization and storage of data. The units communicate to each other wirelessly, via a Bluetooth link, or through a cable. The larger unit processes the incoming data in real time, and warns clinicians (via an audio alarm) of a deterioration of the patient''s condition. The bigger unit can connect to a LAN or the internet so that the REG/EEG data can be downloaded and analyzed offline by clinicians.

* information listed above is at the time of submission.

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