Tracking Head Motion and Orientation in VOR Testing

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$99,446.00
Award Year:
2004
Program:
SBIR
Phase:
Phase I
Contract:
1R43DC007051-01
Award Id:
71465
Agency Tracking Number:
DC007051
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
BARRON ASSOCIATES, INC., 1410 Sachem Place, CHARLOTTESVILLE, VA, 22901
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
B PARKER
(434) 973-1215
PARKER@BARRON-ASSOCIATES.COM
Business Contact:
DAVID WARD
(434) 973-1215
BARRON@BARRON-ASSOCIATES.COM
Research Institution:
n/a
Abstract
The oculomotor response to angular head movement, or the angular vestibulo-ocular reflex (VOR), is a measure of the accuracy of communication between the inner ear and the eyes that has been demonstrated for head rotation in yaw, pitch, and roll. Current "high-frequency" VOR testing methods are insufficient because they fail to take into consideration the effect of otolithic coupling during off-axis head movements - i.e., in the case of not purely horizontal (yawing) or vertical (pitching) head movements. To enable these issues to be properly addressed, we herein propose development of a Kinematic Angular Vestibulo-Ocular Reflex Testing System (KAVORTS) that employs a three-dimensional (3-D) analysis of head motion and orientation during VOR testing in conjunction with the electrooculogram (EOG). Recent advances in the size and performance of micro-electromechanical systems (MEMS)-based inertial sensors enable the development of a device to provide precise information about head motion and orientation during VOR testing. The Phase I effort will also demonstrate - for the first time - computation of vertical eye asymmetry (bias) as a function of head motion, a capability that will facilitate the stratification of patients in terms of lesion location and progress of vestibular pathology.

* information listed above is at the time of submission.

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