Tracking Head Motion and Orientation in VOR Testing
Small Business Information
BARRON ASSOCIATES, INC.
BARRON ASSOCIATES, INC., 1410 Sachem Place, CHARLOTTESVILLE, VA, 22901
AbstractThe oculomotor response to angular head movement, or the angular vestibulo-ocular reflex (VOR), is a measure of the accuracy of communication between the inner ear and the eyes that has been demonstrated for head rotation in yaw, pitch, and roll. Current "high-frequency" VOR testing methods are insufficient because they fail to take into consideration the effect of otolithic coupling during off-axis head movements - i.e., in the case of not purely horizontal (yawing) or vertical (pitching) head movements. To enable these issues to be properly addressed, we herein propose development of a Kinematic Angular Vestibulo-Ocular Reflex Testing System (KAVORTS) that employs a three-dimensional (3-D) analysis of head motion and orientation during VOR testing in conjunction with the electrooculogram (EOG). Recent advances in the size and performance of micro-electromechanical systems (MEMS)-based inertial sensors enable the development of a device to provide precise information about head motion and orientation during VOR testing. The Phase I effort will also demonstrate - for the first time - computation of vertical eye asymmetry (bias) as a function of head motion, a capability that will facilitate the stratification of patients in terms of lesion location and progress of vestibular pathology.
* information listed above is at the time of submission.