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Extending an Open-Source Integrated Data Management Platform to Anxiety Disorders

Award Information
Agency: Department of Health and Human Services
Branch: National Institutes of Health
Contract: 1R43MH102900-01
Agency Tracking Number: R43MH102900
Amount: $446,896.00
Phase: Phase I
Program: SBIR
Solicitation Topic Code: 101
Solicitation Number: PA11-133
Solicitation Year: 2015
Award Year: 2014
Award Start Date (Proposal Award Date): 2014-01-03
Award End Date (Contract End Date): 2015-12-31
Small Business Information
55 Church Street
New Haven, CT 06510-3014
United States
DUNS: 147024876
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 (203) 777-2550
Business Contact
Phone: (203) 777-2550
Research Institution

DESCRIPTION provided by applicant The goal of this application is to empower anxiety disorders researchers to manage share and repurpose their research data more effectively throughout the research lifecycle by delivering an open source integrated data management platform that meets their needs Mental health research has become more complex collaborative and interdisciplinary and sharing and repurposing data for replication and secondary analyses have become increasingly important to the advancement of science These trends require a data management system that enables researchers to continuously integrate heterogeneous data across studies and sites throughout the data management lifecycle allowing the data to be a renewable rather than a disposable resource Although appropriate technology does not yet exist for anxiety disorders research the open source Research Exchange Database RexDB for autism comes close RexDB for autism is the first robust open source system to meet the integrated lifecycle data management needs of autism researchers We propose to make critical enhancements to RexDB that support three major types of anxiety research interventional research such as clinical trials ancillary stuies conducted alongside clinical trials and longitudinal studies that follow up on participants in
one or more clinical trials e g integrated patient registries To achieve our overarching aim we will a identify the features users need by engaging with stakeholders at four evaluation sites to clearly define software requirements b deliver a preliminary version of the software tha empowers users to configure a robust data management system for anxiety research c implement and evaluate new features by soliciting regular stakeholder feedback and usability testing from each of the evaluation sites addressing major gaps via an agile iterative software development process and d build an active community of users among anxiety disorders researchers A data management system that meets the needs of anxiety disorders researchers will likely generalize across a broad spectrum of behavioral and mental health research Success will accelerate research and increase the value of every research dollar spent by the NIH on mental health by transforming research data into a shared renewable resource PUBLIC HEALTH RELEVANCE This project will empower anxiety disorders researchers to make more effective use of the interdisciplinary research data they collect and to more efficiently exchange data with the scientific community We will achieve this goal by delivering free open source software that can easily integrate various kinds of data from different studies to meet the needs of anxiety researchers This software will allow researchers to optimize their use of scarce research dollars and will help accelerate progress in understanding anxiety and other mental disorders

* Information listed above is at the time of submission. *

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