Bacteriophage-based Aerosol Decontaminant for Use in Patient Care Areas

Award Information
Agency:
Department of Defense
Branch
Army
Amount:
$100,000.00
Award Year:
2008
Program:
STTR
Phase:
Phase I
Contract:
W81XWH-08-C-0112
Agency Tracking Number:
A08A-032-0131
Solicitation Year:
2008
Solicitation Topic Code:
A08-T032
Solicitation Number:
2008.A
Small Business Information
BIODETECTION INSTRUMENTS, LLC
535 W. Research Ctr. Blvd., Suite 135, M/S 300, Fayetteville, AR, 72701
Hubzone Owned:
N
Socially and Economically Disadvantaged:
N
Woman Owned:
N
Duns:
125476825
Principal Investigator:
Lisa Bielke
Senior Scientist
(479) 527-9763
lisa.bielke@biodetection-instruments.com
Business Contact:
Calvin Goforth
President
(479) 571-2592
cgoforth@virtual-incubation.com
Research Institution:
CASE WESTERN RESERVE UNIV.
Cynthia Case
Research Office
Cleveland, OH, 44106
(216) 368-5525
Nonprofit college or university
Abstract
Nosocomial transmission of multi-drug-resistant microorganisms in combat support hospitals is a well-recognized and growing problem. BioDetection Instruments proposes a rapid, simple and safe method for reducing contamination in hospital wards with a novel bacteriophage-based aerosol application. Bacteriophages are natural to the environment and pose no risk to humans. The bacteriophage product will have the potential to thoroughly coat and penetrate niches of bacterial reservoirs typically overlooked by standard housekeeping procedures. This Phase I project is focused on isolation and preliminary testing of bacteriophages that can reduce levels of Acinetobacter baumannii calcoaceticus and Klebsiella pneumoniae on stainless steel and Teflon surfaces. Additionally, bacteriophages will be selected to withstand drying to facilitate a lasting effect within the environment.

* information listed above is at the time of submission.

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