SBIR Phase I: A versatile valveless mutlichannel parallel bioassay system

Award Information
Agency: National Science Foundation
Branch: N/A
Contract: 0740847
Agency Tracking Number: 0740847
Amount: $100,000.00
Phase: Phase I
Program: SBIR
Awards Year: 2008
Solicitation Year: N/A
Solicitation Topic Code: EL
Solicitation Number: NSF 00-144
Small Business Information
535 W RESEARCH BLVD,, SUITE 135, M/S 300, FAYETTEVILLE, AR, 72701
DUNS: 125476825
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Xiao-Li Su
 PhD
 (479) 571-2592
 xiaoli.su@biodetection-instruments.com
Business Contact
 Xiao-Li Su
Title: PhD
Phone: (479) 571-2592
Email: xiaoli.su@biodetection-instruments.com
Research Institution
N/A
Abstract
This Small Business Innovation Research Phase I research project will develop a versatile high throughput bioassay system. The proposed system will be built on a patent-pending biosensing technology that has been exclusively licensed from the University of Arkansas. Using this technology, the company has obtained promising preliminary results for rapid and sensitive detection of food-borne pathogens, protein biomarkers, and pesticide residues. The Phase I research will focus on increasing sample throughput, reducing cross-contamination, and simplifying operation by developing a valveless mutichannel parallel bioassay system. The proposed system will consist of an automated sample/reagent delivery module, an easy-to-change multichannel biosensor cartridge, and an interface providing on-cartridge optical detection. Escherichia coli O157:H7, one of the most common and dangerous food-borne pathogens, will be used as the model target for the feasibility study. Microbial contamination of food products by pathogenic bacteria remains a major concern of our society. Food-borne illness affects millions of Americans each year and food producers are required to test their products for pathogens in a timely manner. Although conventional culture methods hypothetically allow the detection of a single cell of specific pathogens, they are extremely time-consuming, typically requiring at least 24 hours and complicated multi-steps to confirm the analysis. They also require laboratory setup and skilled personnel. The need of rapid detection of food pathogens and other important agents has posed a challenge for high throughput bioassays.

* Information listed above is at the time of submission. *

Agency Micro-sites

SBA logo
Department of Agriculture logo
Department of Commerce logo
Department of Defense logo
Department of Education logo
Department of Energy logo
Department of Health and Human Services logo
Department of Homeland Security logo
Department of Transportation logo
Environmental Protection Agency logo
National Aeronautics and Space Administration logo
National Science Foundation logo
US Flag An Official Website of the United States Government