A NEW CLASS OF PHOTO-RESPONSIVE POLYMERS

Award Information
Agency:
National Science Foundation
Branch
n/a
Amount:
$49,993.00
Award Year:
1991
Program:
SBIR
Phase:
Phase I
Contract:
n/a
Award Id:
14276
Agency Tracking Number:
14276
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
Bend Research (Currently BEND RESEARCH, INC.)
64550 Research Rd, Bend, OR, 97701
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
Scott M. Herbig
Dir, Controlled Release Pharm
() -
Business Contact:
() -
Research Institution:
n/a
Abstract
SEVERAL TYPES OF PHOTO-RESPONSIVE POLYMERS HAVE BEEN DEVELOPED OVER THE PAST 10 YEARS. HOWEVER, CURRENT LIMITATIONS (SUCH AS IRREVERSIBILITY, INADEQUATE PHYSICAL CHANGES, AND HIGH EXPENSE) HAVE PREVENTED THEIR WIDESPREAD USE. BEND RESEARCH PROPOSES TO PURSUE A NEW CLASS OF PHOTO-RESPONSIVE POLYMERS FOR USE IN A VARIETY OF APPLICATIONS (E.G., OPTICAL MEMORY DEVICES, ABSORBANTS, SWITCHES IN ROBOTIC SYSTEMS, AND COATINGS FOR PHARMACEUTICALS AND OTHER ACTIVE INGREDIENTS). GIVEN PHASE I LIMITATIONS, WE WILL FOCUS THIS WORK ON CONTROLLED-RELEASEAPPLICATIONS. OUR GOAL IS TO HAVE THESE POLYMERS PROVIDE 1) REVERSIBLE (ON/OFF) RELEASE OF THE ACTIVE INGREDIENT; 2) PULSATILE OR SUSTAINED DELIVERY; 3) CONTROLLABLE RELEASE KINETICS, INDEPENDENT OF THE TRIGGERING MECHANISM; AND 4) EFFICIENT USE OF MANY DIFFERENT ACTIVE INGREDIENTS AT HIGH CONCENTRATIONS. THE PROPOSED TECHNOLOGY USES AZOBENZENE COMPOUNDS AS A "SWITCH" TO CAUSE REVERSIBLE PHOTO-INDUCED CHANGES IN THE POLYMER. WHEN EXPOSED TO ULTRAVIOLET LIGHT, FUNCTIONAL GROUPS ON AN AZOBENZENE COMPOUND AND AN AGENT COMPOUND CAUSECHANGES IN THE PHYSICAL PROPERTIES OF THE POLYMER. THE POLYMER PROPERTIES RETURN TO THEIR ORIGINAL VALUES WHEN NOT EXPOSED TO ULTRAVIOLET LIGHT. THE PROPOSED USE OF AZOBENZENE DIFFERS FROM PREVIOUS DEVELOPMENT EFFORTS IN THATIT DOES NOT RELY SOLELY ON THE ISOMERIZATION OF THE AZOBENZENE COMPOUNDS AS THE CONFORMATIONAL CHANGES IN THE POLYMER.

* information listed above is at the time of submission.

Agency Micro-sites


SBA logo

Department of Agriculture logo

Department of Commerce logo

Department of Defense logo

Department of Education logo

Department of Energy logo

Department of Health and Human Services logo

Department of Homeland Security logo

Department of Transportation logo

Enviromental Protection Agency logo

National Aeronautics and Space Administration logo

National Science Foundation logo
US Flag An Official Website of the United States Government