MEMBRANE-BASED MICROBIAL-OXIDATION PROCESS FOR PHEROMONE PRODUCTION

Award Information
Agency: Department of Agriculture
Branch: N/A
Contract: N/A
Agency Tracking Number: 14747
Amount: $49,994.00
Phase: Phase I
Program: SBIR
Awards Year: 1991
Solicitation Year: N/A
Solicitation Topic Code: N/A
Solicitation Number: N/A
Small Business Information
Bend Research Inc
64550 Research Road, Bend, OR, 97001
DUNS: N/A
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 David C Muchmore
 () -
Business Contact
Phone: () -
Research Institution
N/A
Abstract
IMPROVED METHODS ARE NEEDED TO LIMIT THE COSTLY DAMAGE CAUSED BY FOREST BEETLES THROUGHOUT THE U.S. AND THE WORLD. INSECT PHEROMONES--CHEMICALS THAT CAN BE USED TO CONTROL INSECT BEHAVIOR--ARE AN ATTRACTIVE PEST-CONTROL METHOD BECAUSE OF THEIR SAFETY, SPECIFICITY, AND EFFECTIVENESS. THE USE OF FOREST-BEETLE PHEROMONES HAS BEEN LIMITED, HOWEVER, BY THE LACK OF A COMMERCIALLY PRACTICAL, COST-EFFECTIVE PRODUCTION PROCESS. THE GOAL OF THIS PROGRAM IS TO COMBINE SYNTHESIS OF FOREST-BEETLE PHEROMONES VIA MICROBIAL OXIDATION AND USE OF A MEMBRANE-REACTOR PROCESS TO CREATE A COMMERCIALLY PRACTICAL, ECONOMICAL PRODUCTION PROCESS FOR FOREST-BEETLE PHEROMONES. THE COMBINATION OF THESE TWO TECHNOLOGIES WILL ELIMINATE KEY TECHNICAL OBSTACLES THAT CURRENTLY HAMPER LARGE-SCALE MANUFACTURE OF FOREST-BEETLE PHEROMONES. IN PHASE I, WE WILL SEEK TO DEMONSTRATE THE FEASIBILITY OF OUR APPROACH THROUGH DEVELOPMENT OF A FED-BATCH/MEMBRANE-REACTOR PROCESS TO PRODUCE A COMMERCIALLYVALUABLE TARGET-PHEROMONE, TRANS-VERBENOL, FROM ALPHA-PINENE. ASSUMING SUCCESS IN PHASE I, IN PHASE II WE WILL OPTIMIZE THE PRODUCTION PROCESS FOR TRANS-VERBENOL AND EXAMINE BROADER APPLICATIONS OF THE PROCESS. PHASE II WILL LAY THE GROUND WORK FOR COMMERCIALIZATION OF THE PROCESS IN PHASE III.

* information listed above is at the time of submission.

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