SUBPICOMOLE DETECTION OF PEPTIDES/AMINO ACIDS

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$373,808.00
Award Year:
1985
Program:
SBIR
Phase:
Phase II
Contract:
n/a
Award Id:
518
Agency Tracking Number:
518
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
1205 Kent Ave., West Lafayette, IN, 47906
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
Ronald E. Shoup Ph.d.
(317) 463-2505
Business Contact:
() -
Research Institute:
n/a
Abstract
THIS PROPOSAL IS TO STUDY THE SYNTHETIC METHODS TO INCORPORATE HIGH-SENSITIVITY ELECTROCHEMICALLY ACTIVE FUNCTIONAL GROUPS INTO AMINES, AMINO ACIDS AND PEPTIDES OF BIOLOGICAL ORIGIN. THE PURPOSE OF THIS DERIVATIZATION IS TO PERMIT THE QUANTITATIVE ANALYSIS OF PICOMOLE LEVELS OF THESE COMPOUNDS USING LIQUID CHROMATOGRAPHY COUPLED TO AN ELECTROCHEMICAL SENSOR. PHASE I OF THIS PROPOSAL IS TO STUDY: (1) THE BEST CONDITIONS TO ACHIEVE THE DERIVATIZATIONAND (2) THE CHROMATOGRAPHIC PROPERTIES OF THESE NEW COMPOUNDS.

* information listed above is at the time of submission.

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