WAVE"

Award Information
Agency:
National Science Foundation
Branch
n/a
Amount:
$40,000.00
Award Year:
1985
Program:
SBIR
Phase:
Phase I
Contract:
n/a
Award Id:
2611
Agency Tracking Number:
2611
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
66 Great Valley Pkwy, Great Valley Corp Ctr, Malvern, PA, 19355
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
DR JOHN R FORRO
PHD OF MICROBIOLOGY
(215) 647-8610
Business Contact:
() -
Research Institute:
n/a
Abstract
IT IS PROPOSED TO INCREASE THE UTILITY OF INTRACELLULAR FLUORESCENCE MEASUREMENTS FOR CONTROL OF FERMENTATION AND CELL CULTURE BY CORRECTING ON-LINE FOR BACKGROUND FLUORESCENCE OF THE MEDIA. THIS WILL USE THE CHARACTERISTICS OF THE EVANESCENT WAVE AT THE SURFACE OF AN OPTIC WAVE GUIDE. THE WAVE PENETRATES INTO THE LESS DENSE MEDIUM ONLY TO ABOUT THE DEPTH OF 1/3 TO 1/2 WAVE LENGTH. THE THICKNESS OF MEDIA SWEPT BY THE EVANESCENT WAVE IS MUCH LESS THAN THE SIZE OF A CELL, THEREBY ESSESTIALLY SEPARATINGTHE FLUORESCENCE OF THE MEDIA FROM THAT OF THE CELLS. FIBEROPTICS WILL BE USED IN THE PHASE I STUDY.

* information listed above is at the time of submission.

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