URINARY TRACT INFECTIONS ASSOCIATED WITH URINARY DRAINAGE CATHETERS ARE A SIGNIFICANT CLINICAL PROBLEM RESULTING IN A PROLONGED HOSPITAL STAY AND AN INCREASED MORTALITY RISK.

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$50,000.00
Award Year:
1985
Program:
SBIR
Phase:
Phase I
Contract:
n/a
Agency Tracking Number:
2943
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
Biomaterials International, In
420 Chipeta Way, Suite 160,, Salt Lake City, UT, 84108
Hubzone Owned:
N
Socially and Economically Disadvantaged:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
DENNIS L. COLEMAN
PRINCIPAL INVESTIGATOR
(801) 583-8444
Business Contact:
() -
Research Institution:
n/a
Abstract
URINARY TRACT INFECTIONS ASSOCIATED WITH URINARY DRAINAGE CATHETERS ARE A SIGNIFICANT CLINICAL PROBLEM RESULTING IN A PROLONGED HOSPITAL STAY AND AN INCREASED MORTALITY RISK. THIS PROPOSAL ADDRESSES A FEASIBILITY STUDY TO DETERMINE IF SURFACE MODIFICATION OF THE CATHETER WILL INHIBIT BACTERIAL MIGRATION. THE PROPOSED RESEARCH WILL TEST THE HYPOTHESIS THAT BACTERIAL FIVE DIFFERENT SURFACE TREATMENTS WILL BE APPLIED TO SILICONE RUBBER URINARY CATHETERS TO MINIMIZE BACTERIAL ADHESION. THE CATHETERS WILL BE CHARACTERIZED BY MICROSCOPY, ESCA, AND CONTACT ANGLE ANALYSIS. IN VITRO BACTERIAL MIGRATION WILL BE DETERMINED USING A MIGRATION MODEL DEVELOPED FOR BIOMATERIALS INTERNATIONAL. STABILITY OF THE SURFACE TREATMENTS WILL ALSO BE EVALUATED

* information listed above is at the time of submission.

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