MINIATURIZED RAMAN CLINICAL GAS ANALYZER

Award Information
Agency:
Department of Health and Human Services
Amount:
$49,000.00
Program:
SBIR
Contract:
N/A
Solitcitation Year:
N/A
Solicitation Number:
N/A
Branch:
N/A
Award Year:
1987
Phase:
Phase I
Agency Tracking Number:
7378
Solicitation Topic Code:
N/A
Small Business Information
Biomaterials International Inc
420 Chipeta Way, Suite 160, Salt Lake City, UT, 84108
Hubzone Owned:
N
Woman Owned:
N
Socially and Economically Disadvantaged:
N
Duns:
N/A
Principal Investigator
 RICHARD A VAN WAGENEN
 (801) 583-8444
Business Contact
Phone: () -
Research Institution
N/A
Abstract
A NEED EXISTS TO QUANTITATE ANESTHETIC AND RESPIRATORY GASES(O2, CO2, N2) IN THE OPERATING ROOM. PREVIOUS WORK HAS SHOWN THAT RAMAN LIGHT SCATTERING CAN BE SUCCESSFULLY UTILIZED FOR MOLECULAR GAS ANALYSIS. THE RAMAN SIGNAL FOR EACH GAS CAN BE SEPARATED FROM THE LASER BEAM RAYLEIGH SCATTER VIA FILTER COMBINATIONS, THUS ELIMINATING THE NEED FOR LARGE, EXPENSIVE MONOCHROMATORS. THIS PROPOSAL ADDRESSES THE FEASIBILITY OF UTILIZING A SMALL, LIGHT, INTRACAVITY, FREQUENCY-DOUBLED, DIODE-PUMPED ND:YAG LASER AS AN ALTERNATIVE TO THE LARGE, INEFFICIENT AR(+) LASER USED IN PREVIOUS WORK. A RESEARCH PROTOTYPE WILL BE CONSTRUCTED THAT USES SUCH A COMMERCIALLY AVAILABLE SOLID-STATE LASER. A MULTICHANNEL GAS CELL WILL BE INSERTEDINTO AN INTRACAVITY SPACE, WHICH WILL BE PUMPED BY THIS LASER. THE RAMAN SIGNAL INTENSITY WILL BE DETERMINED FOR THE ABOVE NOTED GASES AND COMPARED TO THE VALUES CALCULATED FROM A SYSTEM-MODELING EQUATION. ACCURACY, SENSITIVITY, SPECIFICITY, AND LINEARITY WILL ALSO BE EVALUATED FOR EACH GAS. SHOULD THIS APPROACH PROVE FEASIBLE, THE USE OF SUCH A LASER WOULD GREATLY REDUCE INSTRUMENT SIZE, WEIGHT, AND COST, THUS MAKING IT MORE WIDELY AVAILABLE TO THE ANESTHESIOLOGY COMMUNITY.

* information listed above is at the time of submission.

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