Prevention of Biofilm Formation--Dental Unit Water Lines

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: 1 R43 DE11221-01,
Agency Tracking Number: 29352
Amount: $528,423.00
Phase: Phase II
Program: SBIR
Awards Year: 1997
Solicitation Year: N/A
Solicitation Topic Code: N/A
Solicitation Number: N/A
Small Business Information
737 Isom Road, San Antonio, TX, 78216
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Debra Krieg
 () -
Business Contact
Phone: () -
Research Institution
We are developing a powdered cold sterilization technology that is rapidly biocidal against bacteriand bacterial and fungal spores, but is neither toxic nor mutagenic to higher organisms. The biocidafor extended periods, is non- corrosive to 200 and 400 grade stainless steel, does not stain or smelless than 1/50th the cost of most current cold sterilant products. We will determine the effectivenedisinfectant for the water lines in dental units (chairs). The biofilm present in dental water linesopportunistic and primary human pathogens, which are continuously released into the water and incorpaerosol created by the dental handpiece (drill). This aerosol is a source of cross contamination betoccupational hazard to dental care providers. Although there has been much discussion about this prodental and microbiology communities, there is currently no satisfactory method for disinfecting dentproduct, Dentacide, is particularly will suited for this task and we anticipate that tests will showeffective in this application.

* Information listed above is at the time of submission. *

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