Novel Skin Barrier to Prevent and Treat Poison Ivy

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$133,731.00
Award Year:
2004
Program:
STTR
Phase:
Phase I
Contract:
1R41AR051618-01
Agency Tracking Number:
AR051618
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
BIOMEDICAL DEVELOPMENT CORPORATION
BIOMEDICAL DEVELOPMENT CORP, 500 SANDAU, STE 200, SAN ANTONIO, TX, 78216
Hubzone Owned:
N
Socially and Economically Disadvantaged:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
H RAWLS
(210) 567-6871
rawls@uthscsa.edu
Business Contact:
GREGG SIEGEL
(210) 308-0636
GSIEGEL@BIODEVCORP.COM
Research Institution:
UNIVERSITY OF TEXAS HLTH SCI CTR SAN ANT

UNIVERSITY OF TEXAS HLTH SCI CTR
SAN ANTONIO, TX, 78229

Nonprofit college or university
Abstract
DESCRIPTION (provided by applicant): Poison ivy/oak dermatitis (also known as Toxicodendron dermatitis) is the most common allergic contact dermatitis in the United States, affecting millions of Americans every year. The prevalence of poison ivy and oak sensitivity in the general adult population ranges from 50 to 70%, and the sensitivity and severity of skin inflammation can range from minor irritation to that which requires medical attention. Topical corticosteroids are the main form of treatment for poison ivy/oak irritations, however the tendency to develop secondary infection can be enhanced by the use of topical or systemic corticosteroids. The goal of this project is to evaluate a patented polymer-based coating technology as both a skin barrier to and treatment for poison ivy and poison oak dermatitis. The innovative coating is expected to provide a safe, antimicrobial, anti-inflammatory skin barrier product that may prevent and treat poison ivy/oak dermatitis. In order to demonstrate feasibility and effectiveness of using the coatings as a barrier and treatment, the following Specific Aims will be pursued: 1. Optimize Coating Formulations and Compound Formulations for Clinical Testing 2. Evaluate Coatings as a Skin Barrier and Treatment for Toxicodendron Dermatitis in Humans

* information listed above is at the time of submission.

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