A SIMPLE, RAPID MEANS FOR IDENTIFYING THE MICROBIAL OR VIRAL PATHOGEN CAUSING DISEASE WOULD ALLOW FOR EARLY AND EFFECTIVE TREATMENT AND PREVENTIVE MEASURES FOR HUMANS FOUND IN SITUATIONS WITHOUT READY ACCESS TO ADVANCED DIAGNOSTIC FACILITIES AND

Award Information
Agency:
National Aeronautics and Space Administration
Branch
n/a
Amount:
$49,000.00
Award Year:
1983
Program:
SBIR
Phase:
Phase I
Contract:
n/a
Award Id:
661
Agency Tracking Number:
661
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
9932 W. 74th Street, Eden Prairie, MN, 55344
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
PATRICK E. GUIRE
PRINCIPAL INVESTIGATOR
() -
Business Contact:
() -
Research Institution:
n/a
Abstract
A SIMPLE, RAPID MEANS FOR IDENTIFYING THE MICROBIAL OR VIRAL PATHOGEN CAUSING DISEASE WOULD ALLOW FOR EARLY AND EFFECTIVE TREATMENT AND PREVENTIVE MEASURES FOR HUMANS FOUND IN SITUATIONS WITHOUT READY ACCESS TO ADVANCED DIAGNOSTIC FACILITIES AND EXPERTISE (E.G., NASA CREW MEMBERS, FIELD SOLDIERS AND CITIZENS OF SPARSELY POPULATED AND UNDERDEVELOPED AREAS). PATHOGEN IDENTIFICATION REQUIRES THE DETERMINATION OF MULTIPLE BIOCHEMICAL CHARACTERISTICS. THIS PROJECT IS AIMED TOWARDS PROVIDING THE CAPABILITY FOR RAPID IDENTIFICATION OF PATHOGENS WITHOUT EXTENSIVE MEDICAL OR LABORATORY EXPERTISE AND FACILITIES. SETS OF MONOCLONAL ANTIBODIES CAPABLE OF SPECIFIC BINDING TO ONE SPECIES OR A CLASS OF PATHOGENS IN A SAMPLE FROM AIR, WATER, FOOD, OR PHYSIOLOGICAL FLUID, ARE COMBINED WITH A SET OF ENZYMES TO PRODUCE A COLOR OR OTHER SIGNAL PATTERN ON A FILTER PAPER OR IN A SET OF ASSAY CONTAINERS. A PORTABLE HOMOGENEOUS MULTI-ENZYME IMMUNOASSAYKIT IS DEVELOPED TO YIELD INCREASED ASSAY INFORMATION CONTENT, SPEED, CONVENIENCE AND SENSITIVITY.

* information listed above is at the time of submission.

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