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Cervical Cancer Diagnosis by Volume Probe Telemicroscopy

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: 1 R43 CA66481-01,
Agency Tracking Number: 29214
Amount: $99,995.00
Phase: Phase I
Program: SBIR
Solicitation Topic Code: N/A
Solicitation Number: N/A
Solicitation Year: N/A
Award Year: 1995
Award Start Date (Proposal Award Date): N/A
Award End Date (Contract End Date): N/A
Small Business Information
100 Inman Street
Cambridge, MA 02139
United States
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 Mark Modell
Business Contact
Research Institution

In the US, incidence of cervical cancer in young whites is increasing and at the present rate willapproximately 20 years, although Pap smear screening has intensified. Incidence in whites and minoriequality; in developing countries, cervical cancer is the most frequent cause of disease and death fthe US, women with atypical smears are evaluated by colposcopic examination and, usually, tissue bioexpensive demands on medical resources. Abnormal Pap smears have a reported false negative rate of 2examinations also are subject to variability in training and experience of the gynecologist. Even exuse a consiSuitent objective measure as a staging aid. Reducing two-stage errors would substantiallyfinancial costs. We aim to demonstrate that a low-cost, non-invasive, non-contacting, visible-lightoptically differentiate cervical intraepethelial neoplasia from normal tissue and other abnormalitieinvasive carcinoma. Differentiation based on depth- discriminated autofluorescence is known to be clcervical dysplasia. The measuring instrument is interfaced with any standard colposcope and will notcolposcopic examination.

* Information listed above is at the time of submission. *

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