DURING THE PAST DECADE, MARIJUANA USE HAS INCREASED DRAMATICALLY AT ALL AGE LEVELS.

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: N/A
Agency Tracking Number: 3342
Amount: $48,970.00
Phase: Phase I
Program: SBIR
Awards Year: 1985
Solicitation Year: N/A
Solicitation Topic Code: N/A
Solicitation Number: N/A
Small Business Information
11 Taft Court, Rockville, MD, 20850
DUNS: N/A
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 JOSEPH K. CHEN
 PRINCIPAL INVESTIGATOR
 (301) 251-0633
Business Contact
Phone: () -
Research Institution
N/A
Abstract
DURING THE PAST DECADE, MARIJUANA USE HAS INCREASED DRAMATICALLY AT ALL AGE LEVELS. CONCERN FOR HEALTH AND SAFETY HAS RESULTED IN A NEED FOR A LOW-COST, RAPID, AND PORTABLE SYSTEM FOR DETECTION OF CANNABIS COMPONENTS IN URINE AND SALIVA AT SENSITIVITY IN THE LOW NANOGRAM PER ML RANGE, AND WITH HIGH SPECIFICITY. MONOCLONAL ANTIBODIES-BASED ENZYME LINKED IMMUNOSORBENT ASSAY (ELISA) WOULD FILL THESE PARTICULAR NEEDS. PHASE I OF THIS STUDY IS DIRECTED TOWARD THE FEASIBILITY OF DEVELOPING TWO TYPES OF HYBRIDOMA CLONES, ONE PRODUCING MONOCLONAL ANTIBODY SPECIFIC TO DELTA-9-TETRAHYDROCANNABINOL (THC) AND THE OTHER SPECIFIC TO 11-NOR-9-CARBOXY-THC, BOTH WITH SENSITIVITY AT LOW TO SUBNANOGRAM RANGE. OUR PHASE II EFFORTS WILL BE DIRECTED TO THE DEVELOPMENT OF AN ELISA KIT FOR RAPID DETECTION OF THC AND ITS

* Information listed above is at the time of submission. *

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