Rapid Antibiotic Susceptibility Testing

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$476,168.00
Award Year:
2003
Program:
SBIR
Phase:
Phase I
Contract:
1R43AI056707-01
Agency Tracking Number:
AI056707
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
BIOSENSE TECHNOLOGIES, INC.
BIOSENSE TECHNOLOGIES, INC., 4 ARROW DR, WOBURN, MA, 01801
Hubzone Owned:
N
Socially and Economically Disadvantaged:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
RONALD RIEDER
(781) 933-3635
RIEDER@BIOSENSETECH.COM
Business Contact:
(781) 933-3635
Research Institution:
n/a
Abstract
DESCRIPTION (provided by applicant): The development of a new method for the diagnostic testing of Mycobacterium tuberculosis having unparalleled speed and simplicity is proposed. The technical approach is based on a novel implementation of impedance sensing to monitor cellular growth with unprecedented sensitivity and stability. This enables results to be obtained directly from sputum samples within a few hours with a simple, inexpensive, and easy to use device ideally suited for mass production. This method also avoids the need for grown cultures, thus reducing the time from sample collection to complete diagnosis by weeks compared to currently used methods. The new method is also applicable to other Category A, B, and C organisms. Feasibility of the proposed diagnostic tool will be demonstrated with antimicrobial drug resistant strains of Mycobacterium smegmatis and Mycobacterium bovis BCG within a 12-month Phase I effort. A Phase II effort will be focused on the development of a prototype instrumentation and clinical testing of multi-drug resistant strains of M. tuberculosis.

* information listed above is at the time of submission.

Agency Micro-sites

US Flag An Official Website of the United States Government