SBIR Phase I: Rapid Antibiotic Susceptibility Testing

Award Information
Agency:
National Science Foundation
Branch
n/a
Amount:
$100,000.00
Award Year:
2003
Program:
SBIR
Phase:
Phase I
Contract:
0319279
Agency Tracking Number:
0319279
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
BioSense Technologies Inc.
4 Arrow Drive, Woburn, MA, 01801
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
Ronald Rieder
() -
Business Contact:
() -
Research Institution:
n/a
Abstract
This Small Business Innovation Research (SBIR)Phase I proposes to develop a new method for antibiotic susceptibility testing having unparalleled speed and simplicity. The technical approach is based on a novel implementation of impedance sensing to monitor cellular growth with unprecedented sensitivity and stability. This enables results to be obtained directly from bacterial suspensions in less than one hour with a simple, inexpensive, and easy to use device ideally suited for mass production. This method avoids the need for growing cultures reducing the time from sample collection to complete diagnosis by weeks compared to currently used methods. In this Phase I project, the feasibility of the proposed diagnostic tool with antimicrobial drug resistant strains of Escherichia coli and Bacillus subtilis will be demonstrated. The commercial application of the proposed product will be as an in-office medical diagnostic. A low-cost and easy-to-use rapid and specific monitor of biological samples has broad application throughout the microbiological testing industry. Specific large markets include rapid techniques for urinary tract infections, testing of mycobacteria, and testing of biological threat agents.

* information listed above is at the time of submission.

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