Rapid Detection of Bacterial Contamination in Platelets
Department of Health and Human Services
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Small Business Information
BIOSENSE TECHNOLOGIES, INC.
BIOSENSE TECHNOLOGIES, INC., 4 ARROW DR, WOBURN, MA, 01801
Socially and Economically Disadvantaged:
AbstractDESCRIPTION (provided by applicant): The development of a rapid and simple method for the diagnostic testing of pathogenic bacteria in platelet products is proposed. The technical approach is based on a novel implementation of impedance sensing to monitor cellular growth with unprecedented sensitivity and stability. This enables results to be obtained directly from platelet samples within hours with a simple, inexpensive, and easy to use device ideally suited for mass production. The innovative method avoid s the need for high cell densities, thus reducing the time from sample collection to detection of bacterial contamination from days to hours. Feasibility of the diagnostic tool will be demonstrated with several of the clinically significant bacterial strai ns which are often implicated in transfusion-related sepsis.
* information listed above is at the time of submission.