NEW INTERFERENCE COLOR SLIDE

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$35,000.00
Award Year:
1987
Program:
SBIR
Phase:
Phase I
Contract:
n/a
Award Id:
7514
Agency Tracking Number:
7514
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
5766 Central Avenue, Boulder, CO, 80301
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
JOHN HANLIN
PRINCIPAL INVESTIGATOR
(303) 447-1605
Business Contact:
() -
Research Institute:
n/a
Abstract
THE NEW INTERFERENCE COLOR SLIDE PROPOSED FOR IMMUNOASSAYS PRODUCES THE DESIRED COLOR CHANGES IN A WET STATE. THIS TECHNIQUE WILL BRING ASSAYS CLOSER TO A ONE-STEP PROCESS THAN EXISTING TECHNOLOGY. WITHOUT THE RINSING AND DRYING STEPS, THE WET TECHNIQUE WILL BE SIMPLER AND FASTER THAN ELISA. THE ENTIRE ASSAY CAN BE CONTAINED INSIDE BE REFLECTED IN THE HANDLING TIME AND END COSTS OF THE TEST. PRELIMINARY CALCULATIONS INDICATE THE WET SLIDE WILL BE THREE TO FOUR TIMES MORE SENSITIVE THAN THE DRY SLIDE; SENSITIVITY WILL BE IN THE RANGE OF 10 NG/CM(2). AFTER THE COMPLETION OF PHASE I, IT WILL BE EVIDENT IF THE PROPOSED SLIDE FUNCTIONS PROPERLY. A AN IMPERMEABLE ENVELOPE, THEREBY REDUCING THE RISK OF CONTAMINATION. THIS TECHNIQUE WILL ALSO LEND ITSELF TO PRODUCING A PANEL TEST WITH A SINGLE APPLIED SAMPLE. THE INHERENT ACCURACY AND REPRODUCIBILITY OF OPTICAL METHODS AND TECHNIQUES ELIMINATES THE DILUTION SERIES AND CONTROLS. THIS ADVANTAGE WILL PRACTICAL ASSAY SYSTEM WILL BE SPECIFIED, AND A COST ESTIMATE CAN BE PRODUCED FOR PHASE II. THIS NEW TECHNIQUE AND RESEARCH OF THE MARKET WILL FORM A BASE FOR COMMERCIAL DEVELOPMENT AND PRODUCTION.

* information listed above is at the time of submission.

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