STTR Phase I: Localized Gene Delivery from Implantable Arterial Devices

Award Information
Agency:
National Science Foundation
Branch
n/a
Amount:
$150,000.00
Award Year:
2007
Program:
STTR
Phase:
Phase I
Contract:
0711141
Agency Tracking Number:
0711141
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
Biosurfaces
171 Main Street, Suite 302, 6745 HOLLISTER AVENUE, Ashland, MA, 01721
Hubzone Owned:
N
Socially and Economically Disadvantaged:
N
Woman Owned:
N
Duns:
131658739
Principal Investigator:
Matthew Phaneuf
Mr
(508) 881-8860
biosurfaces@verizon.net
Business Contact:
Matthew Phaneuf
PhD
(508) 881-8860
biosurfaces@verizon.net
Research Institution:
Beth Israel Deacness Medical Center
Christine A Ferran
330 Brookline Ave
Boston, MA, 2215
(508) 881-8860
Nonprofit college or university
Abstract
This Small Business Technology Transfer (STTR) Phase I research project aims to develop a fibrous material for the embedment and gradual release of appropriate genetic material, including small interfering RNA (siRNA), and viral vectors carrying genes for anti-inflammatory molecules, from coronary stents and prosthetic grafts. With over one million stents, and 70,000 prosthetic grafts placed each year, development of a reliable material that can release biological entities such as viral vectors and siRNA can be of large benefit for the millions of individuals suffering from heart disease and other occlusive ailments.

* information listed above is at the time of submission.

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