THIS PROPOSAL RELATES TO THE DEVELOPMENT OF BIOLUMINESCENT REAGENTS COMPOSED OF FIREFLY OR BACTERIAL LUCIFERASE CONVALENTLY LINKED TO SPECIFIC BINDING PROTEINS (SBP) SUCH AS MONOCLONAL ANTIBODIES, POLYCLONAL ANTIBODIES, LECTINS, AND PROTEIN A.

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$50,000.00
Award Year:
1984
Program:
SBIR
Phase:
Phase I
Contract:
n/a
Award Id:
1392
Agency Tracking Number:
1392
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
2210 Maroneal, Suite 302, Houston, TX, 77030
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
JILL D. FABRICANT
PRESIDENT
() -
Business Contact:
(713) 432-1182
Research Institution:
n/a
Abstract
THIS PROPOSAL RELATES TO THE DEVELOPMENT OF BIOLUMINESCENT REAGENTS COMPOSED OF FIREFLY OR BACTERIAL LUCIFERASE CONVALENTLY LINKED TO SPECIFIC BINDING PROTEINS (SBP) SUCH AS MONOCLONAL ANTIBODIES, POLYCLONAL ANTIBODIES, LECTINS, AND PROTEIN A. THESE CONJUGATES WILL BE EVALUATED AS REAGENTS IN LUMINESCENT IMMUNE ASSAYS (LIA) AND AS IMMUNOLUMINESCENT STAINS (ILS). PROPOSED APPLICATIONS INCLUDE THE IDENTIFICATION AND ASSAY OF MACROMOLECULAR ANTIGENS, SMALL MOLECULES SUCH AS DRUGS OR HORMONES, CELL LABELLING FOR FLOW CYTOMETRY/CELL SORTING AND THE LOCALIZATION AND VISUALIZATION OF ANTIGENS SEPARATED BY ELECTROPHORESIS.

* information listed above is at the time of submission.

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