MULTIPURPOSE CLONING/SUBCLONING SYSTEM

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: N/A
Agency Tracking Number: 7236
Amount: $46,000.00
Phase: Phase I
Program: SBIR
Awards Year: 1987
Solicitation Year: N/A
Solicitation Topic Code: N/A
Solicitation Number: N/A
Small Business Information
Commerce Park, Corporate Drive, Danbury, CT, 06810
DUNS: N/A
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 DALE M RODERICK PHD
 (203) 790-7880
Business Contact
Phone: () -
Research Institution
N/A
Abstract
BIOTIX PROPOSES TO DEVELOP SYSTEMS FOR STABLY CLONING SMALL AND LARGE DNA FRAGMENTS THAT ARE ALSO OPTIMIZED FOR PRODUCING A SERIES OF OVERLAPPING SUBCLONES USING EITHER THESINGLE-STRANDED OR THE DOUBLE-STRANDED PROCEDURE. THE VECTORS WILL BE CONSTRUCTED FROM EXISTING VECTORS UTILIZING A POWERFUL NEW INSERTION TECHNIQUE. SUCCESS IN THE CONSTRUCTION OF THESE VECTOR SYSTEMS WILL LEAD TO THE DEVELOPMENT AND PRODUCTION OF A SERIES OF INTEGRATED KITS DURING PHASE II. THE SPECIFIC PHASE I OBJECTIVES ARE: (1) CONSTRUCTION OF A VECTOR WITH A MULTIPLE CLONING REGION OPTIMIZED FOR BOTH SINGLE- AND DOUBLE-STRANDED SUBCLONING PROCEDURES; AND (2) MODIFICATION OF THE VECTOR TO INCLUDE A COS SITE TO PERMIT UP TO 40 KB FRAGMENTS TO BE STABLY CLONED.

* Information listed above is at the time of submission. *

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