MULTIPURPOSE CLONING/SUBCLONING SYSTEM

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$46,000.00
Award Year:
1987
Program:
SBIR
Phase:
Phase I
Contract:
n/a
Award Id:
7236
Agency Tracking Number:
7236
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
Commerce Park, Corporate Drive, Danbury, CT, 06810
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
DALE M RODERICK PHD
(203) 790-7880
Business Contact:
() -
Research Institute:
n/a
Abstract
BIOTIX PROPOSES TO DEVELOP SYSTEMS FOR STABLY CLONING SMALL AND LARGE DNA FRAGMENTS THAT ARE ALSO OPTIMIZED FOR PRODUCING A SERIES OF OVERLAPPING SUBCLONES USING EITHER THESINGLE-STRANDED OR THE DOUBLE-STRANDED PROCEDURE. THE VECTORS WILL BE CONSTRUCTED FROM EXISTING VECTORS UTILIZING A POWERFUL NEW INSERTION TECHNIQUE. SUCCESS IN THE CONSTRUCTION OF THESE VECTOR SYSTEMS WILL LEAD TO THE DEVELOPMENT AND PRODUCTION OF A SERIES OF INTEGRATED KITS DURING PHASE II. THE SPECIFIC PHASE I OBJECTIVES ARE: (1) CONSTRUCTION OF A VECTOR WITH A MULTIPLE CLONING REGION OPTIMIZED FOR BOTH SINGLE- AND DOUBLE-STRANDED SUBCLONING PROCEDURES; AND (2) MODIFICATION OF THE VECTOR TO INCLUDE A COS SITE TO PERMIT UP TO 40 KB FRAGMENTS TO BE STABLY CLONED.

* information listed above is at the time of submission.

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