BORON BIOLOGICALS, INC.

Basic Information

620 HUTTON ST, STE 104
RALEIGH, NC, 27606

Company Profile

n/a

Additional Details

Field Value
DUNS: n/a
Hubzone Owned: N
Socially and Economically Disadvantaged: N
Woman Owned: N
Number of Employees: n/a


  1. NEW (B22H22)2 FOR NEUTRON CAPTURE AND DIAGNOSTICS

    Amount: $100,000.00

    Not Available Pacific Advanced Technology (PAT) will bring over ten years of experience in spectral imaging to this effort to develop a low cost, lightweight, visible spectral imaging system that wil ...

    SBIR Phase I 1999 Department of Health and Human Services
  2. Selective Silver Staining of DNA Probes

    Amount: $100,000.00

    The major impediment to the wide implementation of DNA diagnostic methods is their cost. Technologisimplify current DNA diagnostic methods and to make them cost competitive with antibody based assaysd ...

    SBIR Phase I 1995 Department of Health and Human Services
  3. P-Carboranylalanine Analogs of BPA for NCT

    Amount: $100,000.00

    Boron Neutron Capture Therapy (BNCT) is a very promising therapy for certain tumors, such as gliomamelanomas. p-Boronophenylalanine (BPA), an analog of phenylalanine, is one of the leading BNCT agentu ...

    SBIR Phase I 1995 Department of Health and Human Services
  4. Boronated Asparagine and Glutamine Analogs for BNCT

    Amount: $79,380.00

    Boron Neutron Capture Therapy (BNCT) has a clear theoretical advantage over other techniquesas a method of delivering cell-killing radiation to tumors. The inability of leukemia cells to synthesizeasp ...

    SBIR Phase I 1994 Department of Health and Human Services
  5. Reproductive Toxicology of Boron Analogs of Biomolecules

    Amount: $73,004.00

    Boron analogs of biomolecules exhibit considerable therapeutic potential in the areas of cancertreatment, bone disorder (such as osteoporosis), hyperlipidemia and inflammation. Considerable activityha ...

    SBIR Phase I 1994 Department of Health and Human Services
  6. NUCLEOSIDE PHOSPHATE ANALOGUES WITH BORONATED PHOSPHATES

    Amount: $483,092.00

    USE OF NUCLEOSIDE PHOSPHATES AS ANTITUMOR AND ANTIVIRAL AGENTS HAS BEEN LIMITED BY THEIR INABILITY TO PENETRATE CELL MEMBRANES AS WELL AS THEIR HIGH SUSCEPTIBILITY TO ENZYMES SUCH AS PHOSPHATASES, NUC ...

    SBIR Phase II 1993 Department of Health and Human Services
  7. NEW GADOLINIUM-BORON COMPOUNDS FOR NEUTRON CAPTURE THERAPY

    Amount: $500,000.00

    NEUTRON CAPTURE THERAPY IS A VERY PROMISING THERAPY FOR CERTAIN TUMORS, SUCH AS GLIOMAS AND MELANOMAS. SEVERAL NUCLEI HAVE HIGH CROSS SECTIONS FOR THERMAL NEUTRONS, OF WHICH BORON-10 ((10)B) AND GADOL ...

    SBIR Phase II 1993 Department of Energy
  8. Amine-Boranes as New Topoisomerase II Inhibitors

    Amount: $50,000.00

    The main objective of the research is to develop a new class of topoisomerase II (Topo II) inhibitors as antineoplastic agents. In preliminary studies, heterocyclic amine-carboxyboranes have been show ...

    SBIR Phase I 1993 Department of Health and Human Services
  9. Boronated Nucleoside Bases

    Amount: $50,000.00

    We will design and synthesize novel nucleic acid base derivatives containing cyanoborane group attached to a pyridine-type nitrogen atom of the purine or the pyrimidine cycle. The cyanoboronated bases ...

    SBIR Phase I 1993 Department of Health and Human Services
  10. Boronic Acid Analogs of Nucleoside-5'-Phosphates

    Amount: $50,000.00

    A major problem with the use of nucleoside phosphates as antiviral and antitumor drugs has been their inability to penetrate cell membranes. Additionally, nucleoside phosphates are susceptible to phos ...

    SBIR Phase I 1993 Department of Health and Human Services

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