BORON BIOLOGICALS, INC.

Company Information

Company Name
BORON BIOLOGICALS, INC.
Address
620 HUTTON ST, STE 104
RALEIGH, NC, 27606
Phone
1 919-832-2044
URL
n/a
DUNS
n/a
Number of Employees
n/a
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N

Award Totals

PROGRAM/PHASE
AWARD AMOUNT ($)
NUMBER OF AWARDS
SBIR Phase I
$902,328.00
14
SBIR Phase II
$2,966,531.00
6
Chart code to be here

Award List

  1. NOVEL BASE BORONATED OLIGONUCLEOTIDES FOR BORON NEUTRON CAPTURE THERAPY

    Amount: $499,885.00

    BORON NEUTRON CAPTURE THERAPY (BNCT) HAS A CLEAR THEORETICALADVANTAGE OVER OTHER TECHNIQUES AS A METHOD OF DELIVERING CELL KILLING RADIATION TO TUMORS. NEW BORON COMPOUNDS ARE NEEDED THAT CAN SELECTIV ...

    SBIR Phase II 1990 Department of Energy
  2. OLIGONUCLEOTIDES WITH BORONATED PHOSPORUS BACKBONES

    Amount: $483,554.00

    THE OBJECTIVE IS TO DEFINE NOVEL OLIGONUCLEOTIDES THAT HAVE PENDANT GROUPS CONTAINING BORON ATTACHED TO PHOSPHORUS IN THE PHOSPHODIESTER BACKBONE. SUCH BORONATED OLIGONUCLEOTIDES MAY FUNCTION AS DESIG ...

    SBIR Phase II 1991 Department of Health and Human Services
  3. NEW BORON CONTAINING AMINO ACIDS AND PEPTIDES FOR BORON NEUTRON CAPTURE THERAPY

    Amount: $500,000.00

    BORON NEUTRON CAPTURE THERAPY (BNCT) HAS A CLEAR THEORETICALADVANTAGE OVER OTHER TECHNIQUES AS A METHOD OF DELIVERING CELL-KILLING RADIATION TO TUMORS. NEW BORON COMPOUNDS ARE NEEDED WHICH CAN SELECTI ...

    SBIR Phase II 1991 Department of Energy
  4. INEXPENSIVE PATHWAYS FOR THE SYNTHESIS OF BORONOPHENYLALANINE AND NEW BORON CONTAINING AGENTS

    Amount: $500,000.00

    BORON NEUTRON CAPTURE THERAPY (BNCT) HAS A CLEAR THEORETICALADVANTAGE OVER OTHER TECHNIQUES AS A METHOD OF DELIVERING CELL-KILLING RADIATION TO CANCEROUS TUMORS. COMPOUNDS CONTAINING THE ELEMENT BORON ...

    SBIR Phase II 1992 Department of Energy
  5. NUCLEOSIDE PHOSPHATE ANALOGUES WITH BORONATED PHOSPHATES

    Amount: $483,092.00

    USE OF NUCLEOSIDE PHOSPHATES AS ANTITUMOR AND ANTIVIRAL AGENTS HAS BEEN LIMITED BY THEIR INABILITY TO PENETRATE CELL MEMBRANES AS WELL AS THEIR HIGH SUSCEPTIBILITY TO ENZYMES SUCH AS PHOSPHATASES, NUC ...

    SBIR Phase II 1993 Department of Health and Human Services
  6. NEW GADOLINIUM-BORON COMPOUNDS FOR NEUTRON CAPTURE THERAPY

    Amount: $500,000.00

    NEUTRON CAPTURE THERAPY IS A VERY PROMISING THERAPY FOR CERTAIN TUMORS, SUCH AS GLIOMAS AND MELANOMAS. SEVERAL NUCLEI HAVE HIGH CROSS SECTIONS FOR THERMAL NEUTRONS, OF WHICH BORON-10 ((10)B) AND GADOL ...

    SBIR Phase II 1993 Department of Energy
  7. Amine-Boranes as New Topoisomerase II Inhibitors

    Amount: $50,000.00

    The main objective of the research is to develop a new class of topoisomerase II (Topo II) inhibitors as antineoplastic agents. In preliminary studies, heterocyclic amine-carboxyboranes have been show ...

    SBIR Phase I 1993 Department of Health and Human Services
  8. Boronated Asparagine and Glutamine Analogs for BNCT

    Amount: $79,380.00

    Boron Neutron Capture Therapy (BNCT) has a clear theoretical advantage over other techniquesas a method of delivering cell-killing radiation to tumors. The inability of leukemia cells to synthesizeasp ...

    SBIR Phase I 1994 Department of Health and Human Services
  9. Reproductive Toxicology of Boron Analogs of Biomolecules

    Amount: $73,004.00

    Boron analogs of biomolecules exhibit considerable therapeutic potential in the areas of cancertreatment, bone disorder (such as osteoporosis), hyperlipidemia and inflammation. Considerable activityha ...

    SBIR Phase I 1994 Department of Health and Human Services
  10. Boronated Nucleoside Bases

    Amount: $50,000.00

    We will design and synthesize novel nucleic acid base derivatives containing cyanoborane group attached to a pyridine-type nitrogen atom of the purine or the pyrimidine cycle. The cyanoboronated bases ...

    SBIR Phase I 1993 Department of Health and Human Services

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