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A Point-of-Care Assay for the Detection of Q fever

Award Information
Agency: Department of Defense
Branch: Army
Contract: W81XWH-09-C-0041
Agency Tracking Number: A2-4016
Amount: $729,998.00
Phase: Phase II
Program: SBIR
Solicitation Topic Code: A08-178
Solicitation Number: 2008.3
Solicitation Year: 2008
Award Year: 2010
Award Start Date (Proposal Award Date): 2010-01-16
Award End Date (Contract End Date): 2012-02-15
Small Business Information
145 North Sierra Madre Blvd., Suite #5
Pasadena, CA -
United States
DUNS: 011114167
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: Yes
Principal Investigator
 Hiep-Hoa Nguyen
 (714) 791-1774
Business Contact
 Sanjay Jayachandran
Title: Vice President
Phone: (626) 535-9496
Research Institution

The objective of this proposal is to develop a highly sensitive point-of-care rapid test assay for the diagnosis of Q-fever. Selected highly immunogenic and unique surface-membrane proteins from Coxiella burnetii, the causative agent for Q-fever will be the basis for the rapid test assay. We will utilize the antigens and antibodies prepared during Phase I to create an improved version of the diagnostic assay capable of detecting Coxiella analyte(s) in the range of pg/ml. Venues to improve the sensitivity and specificity of the assay will be pursued. We envision creating a POC rapid test kit capable of detecting Coxiella-specific antibodies and/or Coxiella-specific antigen in infected subjects'' serum and whole blood.

* Information listed above is at the time of submission. *

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