Iron Man: Novel Technologies for Autonomous Defense

Award Information
Agency:
Department of Defense
Branch
Defense Advanced Research Projects Agency
Amount:
$100,000.00
Award Year:
2009
Program:
STTR
Phase:
Phase I
Contract:
W911NF-09-C-0162
Agency Tracking Number:
A09A-013-0259
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
Caldera Pharmaceuticals, Inc.
278 DP Road, Suite D, Los Alamos, NM, 87544
Hubzone Owned:
N
Socially and Economically Disadvantaged:
N
Woman Owned:
N
Duns:
147452275
Principal Investigator:
Eva Birnbaum
CSO
(505) 412-2345
eva@cpsci.com
Business Contact:
Benjamin Warner
CEO
(505) 412-2345
warner@cpsci.com
Research Institution:
Harvard Medical School
Nicole Touchet
25 Shattuck Street
Boston, MA, 2115
(617) 417-9622
Nonprofit college or university
Abstract
Caldera Pharmaceuticals proposes to develop a highly metal-selective system to maintain iron concentrations in the body at optimal levels to prevent infections. The system will control iron without the loss of other essential micronutrients; loss of micronutrients is the cause of toxicity in most chelation systems. Metal selectivity and the corresponding safety for use is the key difference between Caldera's system and other therapies. Caldera's XRpror will be used to conduct discovery-phase steps. Harvard collaborators will help to design and conduct a human study to determine whether optimal iron levels decrease spontaneous infection rates in a healthy population.

* information listed above is at the time of submission.

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