RESEARCHERS WILL DESCRIBE STUDIES DESIGNED TO DEVELOP SPECIFIC DIAGNOSTIC ASSAYS OF ATRIAL NATRIURETIC FACTOR AND ITS METABOLITES.

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: N/A
Agency Tracking Number: 4968
Amount: $50,000.00
Phase: Phase I
Program: SBIR
Awards Year: 1986
Solicitation Year: N/A
Solicitation Topic Code: N/A
Solicitation Number: N/A
Small Business Information
2450 Bayshore Frontage Rd, Mountain View, CA, 94043
DUNS: N/A
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 DALE B SCHENK
 PRINCIPAL INVESTIGATOR
 (415) 966-1550
Business Contact
Phone: () -
Research Institution
N/A
Abstract
RESEARCHERS WILL DESCRIBE STUDIES DESIGNED TO DEVELOP SPECIFIC DIAGNOSTIC ASSAYS OF ATRIAL NATRIURETIC FACTOR AND ITS METABOLITES. SUCH ASSAYS ARE CURRENTLY NOT AVAILABLE BUT ARE REQUIRED FOR A COMPLETE UNDERSTANDING OF ATRIAL NATRIURETIC FACTOR IN THE REGULATION OF BLOOD PRESSURE. THIS STUDY INVOLVES THE PREPARATION AND USE OF MONOCLONAL ANTIBODIES TO DEFINED REGIONS OF THE PEPTIDE. THE RADIO ANDFLOURIMETRIC ASSAYS DEVELOPED CAN BE UTILIZED TO STUDY THE EXCRETION, FATE, AND METABOLISM OF ANF AND TO SERVE AS DIAGNOSTIC TOOLS TO EXPLORE LIKELY CORRELATIONS BETWEEN CHARACTERISTIC ANF LEVELS AND CERTAIN CARDIOVASCULAR DISORDERS.

* Information listed above is at the time of submission. *

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