CARDIONICS, INC.

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$50,000.00
Award Year:
1985
Program:
SBIR
Phase:
Phase I
Contract:
n/a
Award Id:
3227
Agency Tracking Number:
3227
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
15502 Old Galveston Road, Suit, E 220, Webster, TX, 77598
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
EMILY CAROLYN JOHNSON
PRINCIPAL INVESTIGATOR
(713) 488-3195
Business Contact:
() -
Research Institution:
n/a
Abstract
CARDIONICS, INC. OF HOUSTON, TEXAS IS CURRENTLY PROVIDING A RELATIVELY INEXPENSIVE PORTABLE PULSED DOPPLER (PD) ULTRASONIC UNIT THAT NONINVASIVELY MEASURES CARDIAC OUTPUT (CO) IN HUMANS. USING THERMODILUTION AS THE INVASIVE STANDARD FOR CO DETERMINATION, THIS STUDY WILL COMPARE THE RELATIVE RELIABILITIES AND ACCURACIES OF THE PD DEVICE (CARDIOFLO) AND A COMMERCIALLY AVAILABLE CONTINUOUS WAVE DOPPLER UNIT (CWD) (ULTRACOM). 1. TO DETERMINE WHETHER THIS SIMPLE NONINVASIVE DEVICE CAN ACCURATELY AND RELIABLY MEASURE CO AND 2. TO INVESTIGATE POSSIBLE DESIGN IMPROVEMENTS THAT CAN BE INCORPORATED INTO A SUBSEQUENT MODEL. WE WILL ADDRESS THE RELATIVE ACCURACIES OF SEVERAL METHODS OF OBTAINING AND PROCESSING DOPPLER SPECTRAL SIGNALS. QUADRATURE OUTPUTS WILL BE RECORDED AND SUBSEQUENTLY ANALYZED THROUGH COMPUTER-BASED FAST FOURIER TRANSFORM (FFT) AND ANALOG OFFSET ZEROCROSSER (ZC) UNITS. PAIRED COMPARISONS WILL BE: 1. PD VS. CWD; 2. BASEBAND ZC VS. FFT; 3. BASEBAND ZC VS. OFFSET ZC; 4. ANALOG OR DIGITAL INTEGRATION OF THE ENTIRE CARDIAC CYCLE VS. LEFT VENTRICULAR EJECTION PERIOD ONLY; 5. ANALOG TEMPORAL MEAN OF CONSECUTIVE CYCLES VS. OPERATOR SELECTED CYCLES. PHASE II OF THIS STUDY WILL INCORPORATE THE RESULTS OF PHASE I INTO AN IMPROVED CARDIOFLO UNIT WHICH SHOULD HAVE WIDESPREAD COMMERCIAL APPLICATIONS IN CLINICAL AND RESEARCH SETTINGS WHERE CO IS NEEDED BUT THE COST AND RISKS OF TRADITIONAL INVASIVE METHODS ARE NOT JUSTIFIED.

* information listed above is at the time of submission.

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