DEVELOPMENT OF A BIOSENSOR NANOFLUIDIC PLATFORM FOR INTEGRATION WITH TERAHERTZ SPECTROSCOPIC SYSTEM

Award Information
Agency:
Department of Defense
Branch
Office for Chemical and Biological Defense
Amount:
$69,980.00
Award Year:
2010
Program:
SBIR
Phase:
Phase I
Contract:
W911NF-10-C-0076
Award Id:
96643
Agency Tracking Number:
C101-110-0099
Solicitation Year:
n/a
Solicitation Topic Code:
CBD 10-110
Solicitation Number:
n/a
Small Business Information
2020 Avon CT., Suite 43, Charlottesville, VA, 22902
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
789962656
Principal Investigator:
Oguz Dogan
Principal Investigator
(434) 296-2400
od8a@virginia.edu
Business Contact:
Tatiana Globus
President
(434) 924-7709
globus@vibratess.com
Research Institute:
n/a
Abstract
The goal of this SBIR project is to develop and demonstrate an electrokinetically driven nanofluidic sensor device of the physical size and shape that will allow integration with a THz spectroscopic instrument. The substrate and channel surfaces within the device will be appropriate for the acquisition of THz-frequency spectroscopic features from bio-molecules (e.g., DNA, RNA, proteins) in solutions and for their effective label-free detection and identification. Flow within the device will be controlled, and interactions required for capture or processing of relevant biomolecules for fingerprinting will be incorporated into the same device. The Phase I effort of this project is the development of a conceptual design of a proposed nanofluidic sensor package to demonstrate the feasibility of a biosensor system for biological targets detection. The specification of the requirements for a spectroscopic instrument for the acquisition of THz-frequency spectroscopic features from biomolecules will be created. Preliminary experimental characterization of fluidic channels electrokinetic characteristics and optical efficiency will be conducted. In the Phase II a completely functioning nanofluidic sensor platform will be implemented and combined with THz spectroscopic system. The proposed project will be conducted by Vibratess LLc in close collaboration with Pettit Applied Technologies, and with Lichtenberger Consultanting.

* information listed above is at the time of submission.

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