CERVICAL CANCER DETECTION & SCREENING

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$499,999.00
Award Year:
1984
Program:
SBIR
Phase:
Phase II
Contract:
n/a
Agency Tracking Number:
472
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
Cell Analysis Systems Inc.
826 S. Lincoln, Hinsdale, IL, 60521
Hubzone Owned:
N
Socially and Economically Disadvantaged:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
James Bacus
(312) 655-9566
Business Contact:
() -
Research Institution:
n/a
Abstract
THE LONG-TERM OBJECTIVE OF THIS RESEARCH IS TO APPLY NEW TECHNIQUES OF DIGITAL IMAGE PROCESSING TO THE ANALYSIS OF RED BLOOD CELLS. IT HAS BEEN DEMONSTRATED, IN PRELIMINARY RESEARCH, THAT THESE TECHNIQUES HAVE THE POTENTIAL OF PRECISE AND RAPID MEASUREMENTS OF INDIVIDUAL RED CELLS WITH REGARD TO THEIR HEMOGLOBIN CONTENT, SIZE, SHAPE, AND CENTRALPALLOR. FURTHER, SUBPOPULATIONS OF CELLS CAN BE RIGOROUSLY DEFINED ACCORDING TO CHARACTERISTIC VARIATIONS OF THESE MEASUREMENTS. THESE TECHNIQUES COULD PROVIDE A NEW AND INVESTIGATIVE TOOL FOR CLINICAL MEDICINE, RESULTING IN ENHANCED, MORE EFFICIENT, ANEMIA DIAGNOSIS. THE PRIMARY OBJECTIVES OF THESE STUDIES ARE TO DETERMINE THE OPTIMUM MEASUREMENT WAVELENGTH, AND ASSOCIATED EXTINCTION COEFFICIENT, FOR THE MEASUREMENT OF HEMOGLOBIN IN DRIED RED BLOOD CELLS ON A BLOOD FILM. THESE ARE IMPORTANT CONSTANTS,NECESSARY AS FINAL DESIGN COMPONENTS FOR COMMERCIAL APPLICATION OF THE MEASUREMENT TECHNIQUES. THESE PARAMETERSWILL BE SELECTED WITH DUE CONSIDERATION FOR THE DIFFERENT TYPES OF HEMOGLOBIN PRESENT IN THE RED CELL. THE POTENTIAL COMMERCIAL APPLICATION OF THE PROPOSED RESEARCH IS IN THE AREA OF CLINICAL LABORATORY BLOOD ANALYSIS, INSTRUMENTATION,AND TESTING.

* information listed above is at the time of submission.

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